A single-centre, open-label, phase I trial evaluating the pharmacokinetics of single ascending oral doses of IRL757 in healthy elderly volunteers

2024-515124-36-00 Protocol IRL757C002 Human pharmacology (Phase I) - Other Ended

Start 24 Sep 2024 · End 11 Nov 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol IRL757C002

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 12
Countries 1
Sites 1

Apathy in neurodegenerative disorders

Key facts

Sponsor
Integrative Research Laboratories Sweden AB
Participant type
Healthy volunteers
Age range
65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nervous System Diseases [C10]
Trial duration
24 Sep 2024 → 11 Nov 2024
Decision date (initial)
2024-09-09
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Apathy in neurodegenerative disorders

VersionLevelCodeTermSystem organ class
21.1 PT 10053643 Neurodegenerative disorder 100000004852
20.0 PT 10002942 Apathy 100000004873

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Integrative Research Laboratories Sweden AB

Sponsor organisation
Integrative Research Laboratories Sweden AB
Address
Arvid Wallgrens Backe 20, S Annedal S Annedal
City
Goteborg
Postcode
413 46
Country
Sweden

Scientific contact point

Organisation
Integrative Research Laboratories Sweden AB
Contact name
Chief Medical Officer

Public contact point

Organisation
Integrative Research Laboratories Sweden AB
Contact name
Chief Medical Officer

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Ended 12 1
Rest of world 0

Investigational sites

Sweden

1 site · Ended
CTC Clinical Trial Consultants AB
CTC, Dag Hammarskjolds Vag 10b, Uppsala Domkyrkofors., Uppsala

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Sweden 2024-09-24 2024-11-11 2024-09-24 2024-10-28

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-06-19 Sweden Acceptable
2024-09-06
2024-09-09