Phase 1 first-in-human, single and multiple dosing study of FB301 in healthy female subjects

2024-517539-38-00 Protocol FRB-002 Human pharmacology (Phase I) - First administration to humans Ended

Start 13 Feb 2025 · End 6 Jan 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol FRB-002

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ended
Participants planned 89
Countries 1
Sites 1

Women infertility

Key facts

Sponsor
Freya Biosciences ApS
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Female
Therapeutic area
Diseases [C] - Female Urogenital Diseases and Pregnancy Complications [C13]
Trial duration
13 Feb 2025 → 6 Jan 2026
Decision date (initial)
2025-02-06
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Women infertility

VersionLevelCodeTermSystem organ class
27.1 PT 10021926 Infertility 100000004872

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Freya Biosciences ApS

Sponsor organisation
Freya Biosciences ApS
Address
Fruebjergvej 3
City
Copenhagen Oe
Postcode
2100
Country
Denmark

Scientific contact point

Organisation
Freya Biosciences ApS
Contact name
Clinical Department

Public contact point

Organisation
Freya Biosciences ApS
Contact name
Clinical Department

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 89 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
CRS Clinical Research Services Management GmbH
Clinic, Siemensdamm 65, Siemensstadt, Berlin

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2025-02-13 2026-01-06

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-11-30 Germany Acceptable
2025-01-29
2025-02-06
2 NON SUBSTANTIAL MODIFICATION NSM-1 2025-04-29 Germany Acceptable
2025-01-29
2025-04-29