A Study to Learn About if the Study Medicine Called Ibuzatrelvir changes how the body process the other Medicine Dabigatran Etexilate in healthy adults

2024-517797-14-00 Protocol C5091010 Human pharmacology (Phase I) - Other Ended

Start 19 Nov 2024 · End 16 Jan 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol C5091010

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 20
Countries 1
Sites 1

severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Key facts

Sponsor
Pfizer Inc.
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
19 Nov 2024 → 16 Jan 2025
Decision date (initial)
2024-11-19
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

VersionLevelCodeTermSystem organ class
23.0 PT 10084268 COVID-19 100000004862
23.0 LLT 10084272 SARS-CoV-2 infection 10021881

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Pfizer Inc.

Sponsor organisation
Pfizer Inc.
Address
66 Hudson Boulevard East
City
New York
Postcode
10001-2189
Country
United States

Scientific contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Public contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 20 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
Pfizer Clinical Research Unit
N/A, Route de Lennik 808, B-1070, Brussels

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2024-11-19 2025-01-15 2024-11-22 2024-12-12

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-01 Belgium Acceptable
2024-11-05
2024-11-19
2 SUBSTANTIAL MODIFICATION SM-1 2024-12-11 Belgium Acceptable 2025-01-15