IMMUNOGAST: An umbrella phase 2 trial to assess personalized targeted IMMUNOtherapy-based regimens in recurrent advanced/metastatic GASTric adenocarcinoma patients

2024-517816-31-00 Therapeutic exploratory (Phase II) Ongoing, recruitment ended

Start 19 Mar 2021 · Status Ongoing, recruitment ended · 1 EU/EEA countries · 8 sites

Overview

Sponsor-declared trial summary

Phase Therapeutic exploratory (Phase II)
Status Ongoing, recruitment ended
Participants planned 54
Countries 1
Sites 8

For patients with advanced/metastatic gastric adenocarcinomas in progression

Key facts

Sponsor
Hospices Civils De Lyon
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Neoplasms [C04]
Trial duration
19 Mar 2021 → ongoing
Decision date (initial)
2024-11-17
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2024-517816-31-00
EudraCT number
2020-000297-17
ClinicalTrials.gov
NCT04739202

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

For patients with advanced/metastatic gastric adenocarcinomas in progression

VersionLevelCodeTermSystem organ class
27.0 LLT 10071114 Metastatic gastric adenocarcinoma 10029104

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Hospices Civils De Lyon

Sponsor organisation
Hospices Civils De Lyon
Address
3 Quai Des Celestins, Bp 2251 Bp 2251
City
Lyon Cedex 02
Postcode
69229
Country
France

Scientific contact point

Organisation
Hospices Civils De Lyon
Contact name
Pr Benoit YOU

Public contact point

Organisation
Hospices Civils De Lyon
Contact name
Pr Benoit YOU

Locations

1 EU/EEA country · 8 investigational sites

By country

CountryMS statusPlanned subjectsSites
France Ongoing, recruitment ended 54 8
Rest of world 0

Investigational sites

France

8 sites · Ongoing, recruitment ended
Hospices Civils De Lyon
Hépato-Gastroentérologie, 165 Chemin Du Grand Revoyet, 69310, Pierre Benite
Centre Hospitalier Universitaire De Bordeaux
Hépato-Gastroentérologie, 66 Avenue De Magellan, 33608, Pessac Cedex
Centre Hospitalier Universitaire De Toulouse
Oncologie médicale digestive, 1 Avenue Du Professeur Jean Poulhes, Tsa 50032, Toulouse Cedex 9
Hospices Civils De Lyon
Oncologie médicale, 165 Chemin Du Grand Revoyet, 69310, Pierre Benite
Centr Georges Francois Leclerc
Oncologie médicale, 1 Rue Professeur Marion, 21000, Dijon
Assistance Publique Hopitaux De Paris
Hépato-Gastroentérologie, 1 Avenue Claude Vellefaux, 75010, Paris
Centre Hospitalier Regional De Marseille
Hépatogastroentérologie, 264 Rue Saint Pierre, 13005, Marseille
Hospices Civils De Lyon
Hépatogastroentérologie digestive, 5 Place D Arsonval, 69437, Lyon Cedex 03

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
France 2021-03-19 2024-11-17 2024-11-17

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-08 France Acceptable
2024-11-13
2024-11-17
2 SUBSTANTIAL MODIFICATION SM-1 2026-01-28 France Acceptable
2026-03-05
2026-04-02