A pilot study to assess the impact of ABCB1 on the neuropharmacokinetics of the weak ABCB1 substrate [11C]metoclopramide

2024-517875-19-00 Human pharmacology (Phase I) - First administration to humans Ongoing, recruiting

Start 12 Oct 2017 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ongoing, recruiting
Participants planned 85
Countries 1
Sites 1

Investigation in healthy volunteers and dementia patients (Alzheimers disease)

Key facts

Sponsor
Medical University Of Vienna
Participant type
Healthy volunteers, Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Phenomena and Processes [G] - Biological Phenomena [G16]
Trial duration
12 Oct 2017 → ongoing
Decision date (initial)
2025-01-15
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2024-517875-19-00
EudraCT number
2017-000989-30

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Investigation in healthy volunteers and dementia patients (Alzheimers disease)

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Medical University Of Vienna

Sponsor organisation
Medical University Of Vienna
Address
Spitalgasse 23, Alsergrund Alsergrund
City
Vienna
Postcode
1090
Country
Austria

Scientific contact point

Organisation
Medical University Of Vienna
Contact name
Department of Clinical Pharmacology

Public contact point

Organisation
Medical University Of Vienna
Contact name
Department of Clinical Pharmacology

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Austria Ongoing, recruiting 85 1
Rest of world 0

Investigational sites

Austria

1 site · Ongoing, recruiting
Medical University Of Vienna
Department of Clinical Pharmacology, Waehringer Guertel 18-20, Alsergrund, Vienna

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Austria 2017-10-12 2017-10-12

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-11-21 Austria Acceptable
2025-01-10
2025-01-15