A randomised, assessor-blinded, controlled, healthy volunteer, Phase I study to assess skin irritation and sensitization potential of a novel 5% lidocaine medicated plaster

2024-518038-10-00 Protocol 24EU-Lip03 Human pharmacology (Phase I) - Other Ended

Start 12 May 2025 · End 9 Jan 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol 24EU-Lip03

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 260
Countries 1
Sites 1

None. Healthy subjects

Key facts

Sponsor
IBSA Institut Biochimique SA
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nervous System Diseases [C10]
Trial duration
12 May 2025 → 9 Jan 2026
Decision date (initial)
2025-04-04
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

None. Healthy subjects

VersionLevelCodeTermSystem organ class
21.1 PT 10036376 Post herpetic neuralgia 100000004852

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

IBSA Institut Biochimique SA

Sponsor organisation
IBSA Institut Biochimique SA
Address
Via Pian Scairolo 49
City
Pazzallo
Postcode
6912
Country
Switzerland

Scientific contact point

Organisation
IBSA Institut Biochimique SA
Contact name
Stefano ROVATI

Public contact point

Organisation
IBSA Institut Biochimique SA
Contact name
Guiseppe CELIBERTI

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
France Ended 260 1
Rest of world 0

Investigational sites

France

1 site · Ended
Centre De Pharmacologie Clinique Appliquee A La Dermatologie
CPCAD, 151 Route De Saint Antoine, 06200, Nice

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
France 2025-05-12 2026-01-09 2025-05-12 2025-11-28

Application history

4 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-01-23 France Acceptable
2025-04-04
2025-04-04
2 SUBSTANTIAL MODIFICATION SM-1 2025-09-18 France Acceptable
2025-10-14
2025-10-14
3 NON SUBSTANTIAL MODIFICATION NSM-1 2025-11-12 France Acceptable
2025-10-14
2025-11-12
4 NON SUBSTANTIAL MODIFICATION NSM-2 2025-12-04 France Acceptable
2025-10-14
2025-12-04