MESENCHYMAL STROMAL CELL THERAPY FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME - Validation of Mechanistic Pathways and Clinical Efficacy

2024-518160-13-00 Protocol ARDS-MSC-205 Human pharmacology (Phase I) - First administration to humans Ended

End 15 Apr 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol ARDS-MSC-205

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ended
Participants planned 7
Countries 1
Sites 1

Acute Respiratory Distress Syndrome - ARDS

Key facts

Sponsor
Region Uppsala
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
completed 15 Apr 2026
Decision date (initial)
2024-10-25
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2024-518160-13-00
EudraCT number
2019-004462-18
ClinicalTrials.gov
NCT04447833

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Acute Respiratory Distress Syndrome - ARDS

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Region Uppsala

Sponsor organisation
Region Uppsala
Address
Storgatan 27, Uppsala Domkyrkofors. Uppsala Domkyrkofors.
City
Uppsala
Postcode
753 31
Country
Sweden

Scientific contact point

Organisation
Region Uppsala
Contact name
Oscar Simonsson

Public contact point

Organisation
Region Uppsala
Contact name
Oscar Simonsson

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Ended 7 1
Rest of world 0

Investigational sites

Sweden

1 site · Ended
Region Uppsala
Thoraxkirurgi och anestesi, Storgatan 27, Uppsala Domkyrkofors., Uppsala

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-16 Sweden Acceptable
2024-10-25
2024-10-25