A Phase I, randomized, controlled, Latin-square, open-label study, to evaluate the effect of ADV7103 on gastric pH under fed and fasting conditions in adult healthy participants.

2024-518764-13-00 Protocol B06CS Human pharmacology (Phase I) - Other Ended

Start 25 Feb 2025 · End 18 Mar 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol B06CS

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 12
Countries 1
Sites 1

distal renal tubular acidosis (dRTA)

Key facts

Sponsor
Advicenne
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Male Urogenital Diseases [C12], Diseases [C] - Female Urogenital Diseases and Pregnancy Complications [C13]
Trial duration
25 Feb 2025 → 18 Mar 2025
Decision date (initial)
2025-02-19
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

distal renal tubular acidosis (dRTA)

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Advicenne

Sponsor organisation
Advicenne
Address
262 Rue Du Faubourg Saint Honore
City
Paris
Postcode
75008
Country
France

Scientific contact point

Organisation
Advicenne
Contact name
Didier Laurens, Chief Executive Officer

Public contact point

Organisation
Advicenne
Contact name
Didier Laurens, Chief Executive Officer

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
France Ended 12 1
Rest of world 0

Investigational sites

France

1 site · Ended
Biotrial
Unité Clinique, 7 Rue Jean Louis Bertrand, 35000, Rennes

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
France 2025-02-25 2025-03-18 2025-02-25 2025-03-03

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-25 France Acceptable
2025-01-24
2025-02-19