Treatment of Respiratory Complications Associated with COVID-19, Influenza A, Metapneumovirus, Respiratory Syncytial Virus (RSV) Infection Using Wharton’s Jelly (WJ)-Umbilical Cord (UC) Mesenchymal Stromal Cells (ProTrans®): open Phase IB Clinical Trial

2024-519391-11-00 Protocol Protrans V Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol Protrans V

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 9
Countries 1
Sites 1

Respiratory viral disease

Key facts

Sponsor
NextCell Pharma AB
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Respiratory Tract Diseases [C08], Diseases [C] - Virus Diseases [C02]
Decision date (initial)
2024-11-28
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2024-519391-11-00
EudraCT number
2020-002078-29
ClinicalTrials.gov
NCT04896853

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Respiratory viral disease

VersionLevelCodeTermSystem organ class
21.1 LLT 10067384 Respiratory syncytial virus pneumonitis 10021881
24.0 LLT 10070436 H5N1 influenza 10021881
23.0 PT 10084268 COVID-19 100000004862
20.0 PT 10066226 Metapneumovirus infection 100000004862

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

NextCell Pharma AB

Sponsor organisation
NextCell Pharma AB
Address
Halsovagen 7, Flemingsberg Flemingsberg
City
Huddinge
Postcode
141 57
Country
Sweden

Scientific contact point

Organisation
NextCell Pharma AB
Contact name
Sofia Sisay

Public contact point

Organisation
NextCell Pharma AB
Contact name
Sofia Sisay

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Authorised, recruitment pending 9 1
Rest of world 0

Investigational sites

Sweden

1 site · Authorised, recruitment pending
Universitetssjukhuset Örebro
Department of Cardiology, Respiratory medicine and Physiology, Örebro University Hospital, Universitetssjukhuset Örebro, 701 85, Orebro

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-30 Sweden Acceptable
2024-11-27
2024-11-28
2 SUBSTANTIAL MODIFICATION SM-1 2024-12-19 Sweden Not acceptable
2025-03-31
2025-04-04