A dosimetry trial of uPAR targeted radioligand therapy in patients with glioblastoma

2024-520105-39-00 Protocol 64Cu-DOTA-AE105-201 Human pharmacology (Phase I) - Other Ongoing, recruiting

Start 25 Nov 2025 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites · Protocol 64Cu-DOTA-AE105-201

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ongoing, recruiting
Participants planned 6
Countries 1
Sites 1

Glioblastoma

Key facts

Sponsor
Curasight A/S
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nervous System Diseases [C10]
Trial duration
25 Nov 2025 → ongoing
Decision date (initial)
2025-08-22
Transition trial
No
Low-intervention
No
Rare-disease indication
Yes
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Glioblastoma

VersionLevelCodeTermSystem organ class
20.0 PT 10018337 Glioblastoma multiforme 100000004864

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Curasight A/S

Sponsor organisation
Curasight A/S
Address
Ole Maaloees Vej 3
City
Copenhagen N
Postcode
2200
Country
Denmark

Scientific contact point

Organisation
Curasight A/S
Contact name
Hanne Damgaard Jensen

Public contact point

Organisation
Curasight A/S
Contact name
Medical Director

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Denmark Ongoing, recruiting 6 1
Rest of world 0

Investigational sites

Denmark

1 site · Ongoing, recruiting
Rigshospitalet
Department of Brain and Nerve Surgery, Inge Lehmanns Vej 7, 2100, Copenhagen Oe

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Denmark 2025-11-25 2025-12-11

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-06-17 Denmark Acceptable
2025-08-22
2025-08-22
2 SUBSTANTIAL MODIFICATION SM-1 2026-02-27 Denmark Acceptable
2026-03-20
2026-03-24