A study to Learn If Study Medicines Called Cyclosporine and Clarithromycin Affect How the Body Processes the Other Study Medicine Called PF-07328948 in Healthy Adults.

2024-520126-11-00 Protocol C4921008 Human pharmacology (Phase I) - Other Ended

Start 14 Mar 2025 · End 12 Jun 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol C4921008

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 8
Countries 1
Sites 1

Heart Failure

Key facts

Sponsor
Pfizer Inc.
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Musculoskeletal Diseases [C05]
Trial duration
14 Mar 2025 → 12 Jun 2025
Decision date (initial)
2025-03-13
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Heart Failure

VersionLevelCodeTermSystem organ class
20.0 LLT 10019279 Heart failure 10007541

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Pfizer Inc.

Sponsor organisation
Pfizer Inc.
Address
66 Hudson Boulevard East
City
New York
Postcode
10001-2189
Country
United States

Scientific contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Public contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 8 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
Pfizer Clinical Research Unit
N/A, Route de Lennik 808, B-1070, Brussels

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2025-03-14 2025-06-11 2025-03-19 2025-04-02

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-02-04 Belgium Acceptable
2025-03-11
2025-03-13
2 NON SUBSTANTIAL MODIFICATION NSM-1 2025-05-20 Belgium Acceptable
2025-03-11
2025-05-20