A Study to Learn How Enzalutamide, Apalutamide and Bicalutamide Affect the Way Fezolinetant is Processed by the Body in Men With Prostate Cancer

2024-520286-31-00 Protocol 2693-CL-2101 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 3 sites · Protocol 2693-CL-2101

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 56
Countries 1
Sites 3

Hot Flush

Key facts

Sponsor
Astellas Pharma Global Development Inc.
Participant type
Patients, Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male
Therapeutic area
Diseases [C] - Male Urogenital Diseases [C12]
Decision date (initial)
2026-04-03
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Hot Flush

VersionLevelCodeTermSystem organ class
21.1 PT 10060800 Hot flush 100000004866

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Astellas Pharma Global Development Inc.

Sponsor organisation
Astellas Pharma Global Development Inc.
Address
2375 Waterview Drive
City
Northbrook
Postcode
60062-6145
Country
United States

Scientific contact point

Organisation
Astellas Pharma Global Development Inc.
Contact name
RA Clinical Trial Unit Head

Public contact point

Organisation
Astellas Pharma Global Development Inc.
Contact name
RA Clinical Trial Unit Head

Locations

1 EU/EEA country · 3 investigational sites

By country

CountryMS statusPlanned subjectsSites
Bulgaria Authorised, recruitment pending 56 3
Rest of world 0

Investigational sites

Bulgaria

3 sites · Authorised, recruitment pending
Complex Oncology Center Burgas EOOD
First Department of Medical Oncology, 7th Floor, Ulitsa Stefan Stambolov 73, Burgas
Medical Center Comac Medical Ltd.
NA, Ulitsa Urvich 13, Krasno Selo District, Sofia
Medical Center Comac Medical Ltd.
NA, Ulitsa Sveti Georgi Sofiyski 3, 1606, Sofia

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-11-24 Bulgaria Acceptable
2026-03-26
2026-04-03