Neurogenic inflammation upon AITC-induced TRPA1 activation

2025-520494-40-00 Protocol S70063 Human pharmacology (Phase I) - Other Ended

Start 4 Mar 2025 · End 21 Apr 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol S70063

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 25
Countries 1
Sites 1

Not applicable; this trial investigates a physiological process in healthy volunteers.

Key facts

Sponsor
UZ Leuven
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male
Therapeutic area
Phenomena and Processes [G] - Physiological processes [G07]
Trial duration
4 Mar 2025 → 21 Apr 2026
Decision date (initial)
2025-02-26
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Not applicable; this trial investigates a physiological process in healthy volunteers.

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

UZ Leuven

Sponsor organisation
UZ Leuven
Address
Herestraat 49
City
Leuven
Postcode
3000
Country
Belgium

Scientific contact point

Organisation
UZ Leuven
Contact name
Heleen Marynissen

Public contact point

Organisation
UZ Leuven
Contact name
Heleen Marynissen

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 25 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
UZ Leuven
Center for Clinical Pharmacology, Herestraat 49, 3000, Leuven

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2025-03-04 2026-04-21 2025-03-07

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-01-23 Belgium Acceptable
2025-02-25
2025-02-26
2 NON SUBSTANTIAL MODIFICATION NSM-1 2026-04-03 Belgium Acceptable
2025-02-25
2026-04-03