Randomised, crossover bioequivalence clinical trial of escitalopram 20 mg capsules versus escitalopram 20 mg film-coated tablets, after a single oral dose administration to healthy volunteers under fasting conditions

2025-521069-28-00 Protocol UECHUP-ESC/25-1 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 21 Mar 2025 · End 16 Apr 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol UECHUP-ESC/25-1

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 24
Countries 1
Sites 1

Antidepressants

Key facts

Sponsor
Alter Farmacia S.A.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Psychiatry and Psychology [F] - Mental Disorders [F03]
Trial duration
21 Mar 2025 → 16 Apr 2025
Decision date (initial)
2025-03-04
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Antidepressants

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Alter Farmacia S.A.

Sponsor organisation
Alter Farmacia S.A.
Address
Calle De Mateo Inurria 30
City
Madrid
Postcode
28036
Country
Spain

Scientific contact point

Organisation
Alter Farmacia S.A.
Contact name
Carmen Morillo Alonso

Public contact point

Organisation
Alter Farmacia S.A.
Contact name
Carmen Morillo Alonso

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Spain Ended 24 1
Rest of world 0

Investigational sites

Spain

1 site · Ended
Hospital Universitario De La Princesa
Pharmacology, Calle De Diego De Leon 62, 28006, Madrid

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Spain 2025-03-21 2025-03-24 2025-04-08

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-02-21 Spain Acceptable
2025-03-04
2025-03-04
2 NON SUBSTANTIAL MODIFICATION NSM-1 2025-03-14 Spain Acceptable
2025-03-04
2025-03-14