A research study looking at how NNC0487-0111 affects food intake, appetite and metabolism after meals in people with obesity

2025-521393-34-00 Protocol NN9490-8151 Human pharmacology (Phase I) - Other Ongoing, recruiting

Start 19 Mar 2026 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites · Protocol NN9490-8151

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ongoing, recruiting
Participants planned 120
Countries 1
Sites 1

Participants with obesity, but otherwise healthy

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Not possible to specify
Trial duration
19 Mar 2026 → ongoing
Decision date (initial)
2026-03-13
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2025-521393-34-00
WHO UTN
U1111-1319-9246

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Participants with obesity, but otherwise healthy

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission HUB

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission HUB

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ongoing, recruiting 120 1
Rest of world 0

Investigational sites

Germany

1 site · Ongoing, recruiting
PAREXEL International GmbH
Parexel Early Phase Unit Berlin, Klinikum Westend Haus 31, Spandauer Damm 130, Berlin

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2026-03-19 2026-03-30

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-01-14 Germany Acceptable
2026-03-09
2026-03-13