A study to Learn How Safe AGMB-129 is in Healthy Adults Taking Multiple Doses of AGMB-129 That Are Increased a Little at a Time

2025-521705-40-00 Protocol AGMB129-01-CL-109 Human pharmacology (Phase I) - Other Ended

Start 18 Jul 2025 · End 15 Sep 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol AGMB129-01-CL-109

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 40
Countries 1
Sites 1

Fibrostenotic Crohn’s disease

Key facts

Sponsor
Agomab Spain S.L.U.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Digestive System Diseases [C06]
Trial duration
18 Jul 2025 → 15 Sep 2025
Decision date (initial)
2025-06-26
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Fibrostenotic Crohn’s disease

VersionLevelCodeTermSystem organ class
24.1 LLT 10086076 Fibrostenotic Crohn´s disease 100000004848

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Agomab Spain S.L.U.

Sponsor organisation
Agomab Spain S.L.U.
Address
Parque Empresarial De Touro Parcelas 26-27, Fonte Diaz Fonte Diaz
City
A Coruna
Postcode
15822
Country
Spain

Scientific contact point

Organisation
Agomab Spain S.L.
Contact name
Clinical Operations

Public contact point

Organisation
Agomab Spain S.L.
Contact name
Clinical Operations

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 40 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
SGS Belgium
SGS-Clinical Research CPU, Drie Eikenstraat 655, 2650, Edegem

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2025-07-18 2025-09-15 2025-07-18 2025-09-15

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-05-16 Belgium Acceptable
2025-06-26
2025-06-26
2 NON SUBSTANTIAL MODIFICATION NSM-1 2025-09-17 Belgium Acceptable
2025-06-26
2025-09-17