A Study to Learn How Different Forms of The Study Medicine Called Prazosin Are Taken up Into the Blood in Healthy Adults

2025-522574-36-00 Protocol A0281007 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 4 Nov 2025 · End 1 May 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol A0281007

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 72
Countries 1
Sites 1

Primary and secondary hypertension, and heart failure

Key facts

Sponsor
Pfizer Inc.
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Cardiovascular Diseases [C14]
Trial duration
4 Nov 2025 → 1 May 2026
Decision date (initial)
2025-10-10
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Primary and secondary hypertension, and heart failure

VersionLevelCodeTermSystem organ class
21.1 PT 10039834 Secondary hypertension 100000004866
20.0 LLT 10019279 Heart failure 10007541
21.1 LLT 10036695 Primary hypertension 10047065

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Pfizer Inc.

Sponsor organisation
Pfizer Inc.
Address
66 Hudson Boulevard East
City
New York
Postcode
10001-2189
Country
United States

Scientific contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Public contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 72 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
Pfizer Clinical Research Unit
N/A, Route de Lennik 808, B-1070, Brussels

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2025-11-04 2026-04-30 2025-11-14 2026-03-24

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-09-04 Belgium Acceptable
2025-10-08
2025-10-10