Food effect and single- and multiple-ascending dose clinical trial of DF2755A in healthy participants

2025-522935-32-00 Protocol DF2755A-HV-101 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol DF2755A-HV-101

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 56
Countries 1
Sites 1

interstitial cystitis/bladder pain syndrome

Key facts

Sponsor
Dompe' Farmaceutici S.p.A.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Pathological Conditions, Signs and Symptoms [C23], Diseases [C] - Female Urogenital Diseases and Pregnancy Complications [C13], Diseases [C] - Male Urogenital Diseases [C12]
Decision date (initial)
2025-10-17
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

interstitial cystitis/bladder pain syndrome

VersionLevelCodeTermSystem organ class
20.1 PT 10011796 Cystitis interstitial 100000004857

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Dompe' Farmaceutici S.p.A.

Sponsor organisation
Dompe' Farmaceutici S.p.A.
Address
Via Santa Lucia 6
City
Milan
Postcode
20122
Country
Italy

Scientific contact point

Organisation
Dompe' Farmaceutici S.p.A.
Contact name
Pier Adelchi Ruffini

Public contact point

Organisation
Dompe' Farmaceutici S.p.A.
Contact name
Riccardo Vecchietti

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Netherlands Authorised, recruitment pending 56 1
Rest of world 0

Investigational sites

Netherlands

1 site · Authorised, recruitment pending
Pharmaceutical Research Associates Group B.V.
Program Management, Van Swietenlaan 6, 9728 NZ, Groningen

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-09-15 Netherlands Acceptable
2025-10-17
2025-10-17