A study to compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 with US-Dupixent®, and EU-Dupixent® in Healthy Adult Participants.

2025-523115-11-00 Protocol A160_01AD2502 Human pharmacology (Phase I) - First administration to humans Ongoing, recruiting

Start 14 Jan 2026 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites · Protocol A160_01AD2502

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ongoing, recruiting
Participants planned 519
Countries 1
Sites 1

Phase I study in healthy participants. Intended indication: atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, prurigo nodularis, and chronic obstructive pulmonary disease

Key facts

Sponsor
Chong Kun Dang Pharmaceutical Corp.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Immune System Diseases [C20]
Trial duration
14 Jan 2026 → ongoing
Decision date (initial)
2026-01-09
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Phase I study in healthy participants. Intended indication: atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, prurigo nodularis, and chronic obstructive pulmonary disease

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Chong Kun Dang Pharmaceutical Corp.

Sponsor organisation
Chong Kun Dang Pharmaceutical Corp.
Address
8 Chungjeong-Ro
City
Seodaemun
Postcode
03742
Country
Korea, Republic of

Scientific contact point

Organisation
Chong Kun Dang Pharmaceutical Corp.
Contact name
New drug / Bio RA team

Public contact point

Organisation
Chong Kun Dang Pharmaceutical Corp.
Contact name
New drug / Bio RA team

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ongoing, recruiting 335 1
Rest of world
United Kingdom
184

Investigational sites

Germany

1 site · Ongoing, recruiting
PAREXEL International GmbH
01, Klinikum Westend Haus 31, Spandauer Damm 130, Berlin

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2026-01-14 2026-01-23

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-10-29 Germany Acceptable
2026-01-07
2026-01-09