A study to investigate the pharmacokinetics and safety of KM04 compared to US-Gonal-f RFF Redi-ject and EU-Gonal-f in healthy adult female volunteers

2025-523368-19-00 Protocol KM04-101 Human pharmacology (Phase I) - Bioequivalence study Not authorised

Status Not authorised · 1 EU/EEA countries · 1 sites · Protocol KM04-101

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Not authorised
Participants planned 48
Countries 1
Sites 1

Functional female infertility

Key facts

Sponsor
Xentria Inc.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Female
Therapeutic area
Phenomena and Processes [G] - Reproductive and Urinary Physiological Phenomena [G08]
Decision date (initial)
2026-03-23
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Functional female infertility

VersionLevelCodeTermSystem organ class
27.1 PT 10021926 Infertility 100000004872
20.0 PT 10021928 Infertility female 100000004872
27.1 LLT 10016398 Female infertility 10038604

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Xentria Inc.

Sponsor organisation
Xentria Inc.
Address
2032 North Clybourn Avenue Suite 100
City
Chicago
Postcode
60614-4051
Country
United States

Scientific contact point

Organisation
Xentria Inc.
Contact name
Tom Matthews

Public contact point

Organisation
Xentria Inc.
Contact name
Noopur Singh

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Poland Not authorised 48 1
Rest of world 0

Investigational sites

Poland

1 site · Not authorised
Biokinetica S.A.
Przychodnia Jozefow, Ul. Nadwislanska 37, 05-410, Jozefow

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-11-13 Poland Not acceptable
2026-03-16
2026-03-23