A study to learn about how a new nurandociguat tablet is absorbed and processed in the body compared to an old tablet and how food affects the way the new tablet is absorbed and processed in the body

2025-524176-36-00 Protocol 22700 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol 22700

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 18
Countries 1
Sites 1

Chronic Kidney Disease

Key facts

Sponsor
Bayer AG
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Cardiovascular Diseases [C14]
Decision date (initial)
2026-03-25
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Chronic Kidney Disease

VersionLevelCodeTermSystem organ class
23.1 PT 10064848 Chronic kidney disease 100000004857

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Bayer AG

Sponsor organisation
Bayer AG
Address
-
City
Leverkusen
Postcode
51368
Country
Germany

Scientific contact point

Organisation
Bayer AG
Contact name
Therapeutic Area Head

Public contact point

Organisation
Bayer AG
Contact name
Therapeutic Area Head

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Authorised, recruitment pending 18 1
Rest of world 0

Investigational sites

Germany

1 site · Authorised, recruitment pending
CRS Clinical Research Services Berlin GmbH
-, Siemensdamm 65, Siemensstadt, Berlin

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-01-28 Germany Acceptable
2026-03-19
2026-03-25
2 NON SUBSTANTIAL MODIFICATION NSM-1 2026-03-25 Germany Acceptable
2026-03-19
2026-03-25