Randomized, open-label, laboratory-blinded, balanced, single dose, 3-treatment, 6-sequence, 3-period crossover comparative bioavailability study comparing Finerenone, 20 mg, film-coated tablets (Prototype 1, Prototype 2) and Kerendia, 20 mg, film-coated tablets under fasting conditions in healthy participants.

2026-525256-29-00 Protocol RDW483/0155/2 Human pharmacology (Phase I) - Other Ended

Start 13 Mar 2026 · End 9 Apr 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol RDW483/0155/2

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 36
Countries 1
Sites 1

Comparative bioavailability study under fasting conditions

Key facts

Sponsor
Zaklady Farmaceutyczne Polpharma S.a.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Cardiovascular Diseases [C14]
Trial duration
13 Mar 2026 → 9 Apr 2026
Decision date (initial)
2026-03-04
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Comparative bioavailability study under fasting conditions

VersionLevelCodeTermSystem organ class
28.0 SOC 10038359 Renal and urinary disorders 18

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Zaklady Farmaceutyczne Polpharma S.a.

Sponsor organisation
ZAKLADY FARMACEUTYCZNE POLPHARMA S.A.
Address
Ul. Pelplinska 19
City
Starogard Gdanski
Postcode
83-200
Country
Poland

Scientific contact point

Organisation
ZAKLADY FARMACEUTYCZNE POLPHARMA S.A.
Contact name
Clinical R&D

Public contact point

Organisation
ZAKLADY FARMACEUTYCZNE POLPHARMA S.A.
Contact name
Clinical R&D

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Czechia Ended 36 1
Rest of world 0

Investigational sites

Czechia

1 site · Ended
Quinta-Analytica s.r.o.
Clinical Unit, Umelecka 305/1, Moravska Ostrava, Moravska Ostrava A Privoz

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Czechia 2026-03-13 2026-04-09 2026-03-13 2026-03-26

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-02-04 Czechia Acceptable
2026-03-04
2026-03-04