Exploratory, non-randomized, 3-group, microdosing clinical trial to investigate Gallium-68 (68Ga) labeled Platelet-Derived Growth Factor Beta (PDGFRß) targeting Positron Emission Tomography (PET) tracer (68Ga-ATH001) binding in the lungs in healthy participants versus participants with Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD)

2026-525309-11-00 Protocol INT010 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 2 sites · Protocol INT010

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 15
Countries 1
Sites 2

Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD)

Key facts

Sponsor
Antaros Medical AB
Participant type
Patients, Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01]
Decision date (initial)
2026-03-11
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD)

VersionLevelCodeTermSystem organ class
20.0 PT 10042954 Systemic sclerosis pulmonary 100000004855
21.0 LLT 10025109 Lung involvement in systemic sclerosis 10038738

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Antaros Medical AB

Sponsor organisation
Antaros Medical AB
Address
Forandringens Gata 10
City
Molndal
Postcode
431 53
Country
Sweden

Scientific contact point

Organisation
Antaros Medical AB
Contact name
Lars Johansson

Public contact point

Organisation
Antaros Medical AB
Contact name
Lars Johansson

Locations

1 EU/EEA country · 2 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Authorised, recruitment pending 15 2
Rest of world 0

Investigational sites

Sweden

2 sites · Authorised, recruitment pending
CTC Clinical Trial Consultants AB
CTC, Ingang 85 Vaning 2, 751 85, Uppsala
Uppsala University Hospital
Section of rheumatology, Akademiska Sjukhuset, 751 85, Uppsala

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-02-13 Sweden Acceptable
2026-03-10
2026-03-11