Heart failure with reduced ejection fraction

• A Phase I-IIa Trial on the Safety and Preliminary Effectiveness of Intramyocardial Injection of Allogeneic Cardiac Atrial Stem Cells for the … Not authorised
  2024-517031-51-00 7 "Heart Failure"
• Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction Recruiting
  2024-519219-32-00 5 2025-06-23 "Heart Failure With Reduced Ejection Fraction"
• Use of determination of drug levels to optimize pharmacotherapy of heart failure Recruiting
  2023-506283-13-00 6 2024-04-09 "Chronic heart failure with reduced ejection fraction"
• FIT-HF - Effect of weight loss on physical and cardiac performance in patients with heart failure and obesity Recruiting
  2023-503753-35-01 4 2024-03-20 "Obesity and Heart Failure with reduced Ejection Fracition"
• A Phase 2a, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety and Tolerabilit … Recruiting
  2023-504835-42-00 4 2024-02-29 "Heart Failure (Heart Failure with Reduced Ejection Fraction)"
• ARETHA: cARdiomems vEriciguaT Heart fAilure (A double-blind randomized placebo-controlled trial of vericiguat in heart failure patients with … Ended
  2024-514111-10-00 6 2024-12-06 "Heart failure with reduced ejection fraction (HFrEF)"
• A Phase 1b, Double-blind, Placebo-controlled, Randomised Trial Investigating the Effect of AZD3427 on Renal Perfusion in HFrEF Patients With … Ended
  2024-513143-82-00 3 2024-10-15
• A Phase 2 Dose-Finding Study to Assess the Safety and Effectiveness of Tovinontrine in Patients With Chronic Heart Failure With Reduced Ejec … Ended
  2023-508736-62-00 4 2024-08-08 "Heart failure (HF) with reduced ejection fraction (HFrEF)"
• A study to learn how safe starting vericiguat at a dose of 5 milligrams is in participants with chronic heart failure with reduced ejection … Ended
  2023-507682-25-00 4 2024-05-13 "Chronic heart failure with reduced ejection fraction"
• Initiation of angiotensin receptor-neprilysin inhibitor (ARNi) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) in patients with heart … Ended
  2022-502409-14-00 11 2023-08-04
• A study to compare how much of the study treatment finerenone gets into the blood when the same amount is taken in one and in two tablets in … Ended
  2022-502385-24-00 2 2023-04-27 "Heart failure with left ventricular ejection fraction ≥40%"
• Safety and Tolerability of AC01 in patients with heart failure Ended
  2022-500347-20-00 9 2023-02-23 "Heart Failure"
• Phase 2 Study to Assess Efficacy and Safety of CDR132L in Patients with Reduced Left Ventricular Ejection Fraction (≤45%) After Myocardial I … Ended
  2023-507569-24-00 4 2022-06-20 "Myocardial Infarction, Acute Heart Failure, Left Sided"
• A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) Ended
  2022-500881-80-00 5 2021-10-29 "Chronic Heart Failure With Reduced Ejection Fraction"

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