systemic sclerosis Clinical Trials EU — 13 Studies

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Comparison of treatment efficacy in the patients with Systemic sclerOsis: dapagliFlozin vs. Tocilizumab – a randomized head to head study Not authorised

2025-523714-92-00 4
Investigating the (autoreactive) B cell compartment in antibody-mediated autoimmune diseases in comparison with the recall Tetanus Toxoid re … Pending

2024-515312-50-00 6
Efficacy and safety of repeated Rituximab infusions in patients with Active Systemic SClerosis and background medication, a one year randomi … Recruiting

2025-520483-17-01 6 2025-09-02
A Phase 1 Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants with Severe, Refractory Autoimmune Diseases Recruiting

2024-517681-41-00 1 2025-08-29
A study to assess the efficacy and safety of efgartigimod PH20 SC in adults with systemic sclerosis (eSScape) Recruiting

2024-514539-67-00 4 2025-06-27
Phase I/II randomized clinical trial of allogeneic adipose tissue-derived mesenchymal stromal cells systemic infusion in severe systemic scl … Recruiting

2023-505977-34-00 4 2025-01-08
MANUS trial Recruiting

2024-515387-31-00 4 2024-11-01
CAR-T cells in systemic B cell mediated autoimmune disease - CASTLE Recruiting

2024-516819-24-00 9 2023-05-16
SUBCUTANEOUS INJECTIONS OF AUTOLOGOUS CULTURED ADIPOSE-DERIVED STROMA/ STEM CELLS TO HEAL REFRACTORY ISCHEMIC DIGITAL ULCERS IN PATIENTS WIT … Recruiting

2023-508432-53-00 4 2020-09-22
A study to find if tibulizumab works and how safe it is in participants with systemic sclerosis Recruitment ended

2024-519335-42-01 4 2025-12-22
A Phase 1 Study of CD19-targeted NEX-T CAR T Cells in Participants with Severe, Refractory Autoimmune Diseases (Breakfree-1) Halted

2023-503823-24-01 3 2024-04-15
A study in people with systemic sclerosis to test whether BI 685509 has an effect on lung function and other systemic sclerosis symptoms Ended

2022-500332-11-00 4 2022-11-25
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Doses of RO7303509 in Patients with Systemic Sclero … Ended

2022-502981-26-00 3 2022-06-27

Showing 1–13 of 13 trials