Cobimetinib — Drug Intelligence | 10 EU Trials

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10 Registered trials

7 Recruiting

3 Completed trials

9 Sponsors

16 Countries

Phase III

Phase II

Phase I/II

Phase III: 1 Phase II: 8 Phase I/II: 1

Oversight events:

1 serious breach 2 urgent safety measures across 2 trials

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Indications tested

Non-small cell lung cancer 1 Renal cell carcinoma 1 Triple negative breast cancer 1 Ovarian epithelial cancer 1 Ovarian cancer 1 Squamous cell carcinoma of head and neck 1 Non-small cell lung cancer stage IV 1 Skin cancer 1

Sponsors using this IMP

F. Hoffmann-La Roche AG 2 Cancer Research UK 1 Centre Leon Berard 1 Fondazione Melanoma Onlus 1 Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting 1 HUS-Yhtymae 1 Oslo University Hospital HF 1 Rigshospitalet 1 Universita' Degli Studi Di Perugia 1

All trials

10 total

A Phase II trial of ginisortamab in participants with metastatic pancreatic ductal adenocarcinoma Recruiting

2024-514129-43-00 Phase II 3 countries Cancer Research UK
FINPROVE - The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs Recruiting

2024-517478-68-01 Phase II 1 country HUS-Yhtymae
Improving public cancer care by implementing precision medicine in Norway Recruiting

2023-507894-16-00 Phase II 1 country Oslo University Hospital HF
“A phase II randomized non-comparative study, with NEOadjuvant plus adjuvant Therapy with combination or sequence of vemurafenib, cobImetini… Recruiting

2024-516659-41-00 Phase II 1 country Fondazione Melanoma Onlus
ProTarget - A Danish Nationwide Clinical Trial on Targeted Anti‐Cancer Treatment based on Genomic Profiling Recruiting

2023-510527-29-00 Phase II 1 country Rigshospitalet
A multicentre trial evaluating the combination of a MEK inhibitor and a PDL1 inhibitor in pediatric and adult patients with locally advance… Recruiting

2024-510712-75-00 Phase I/II 1 country Centre Leon Berard
DRUP trial Recruiting

2023-509152-33-00 Phase II 1 country Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
STEP-WISE COMBINATION OF OBINUTUZUMAB, VEMURAFENIB AND COBIMETINIB IN PATIENTS WITH HAIRY CELL LEUKEMIA (HCL) PREVIOUSLY TREATED WITH PURINE… Ended

2024-520121-36-00 Phase II 1 country Universita' Degli Studi Di Perugia
A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tu… Ended

2023-508194-89-00 Phase II 5 countries F. Hoffmann-La Roche AG
An open label, multicenter extension study in patients previously enrolled in a Genentch and/or F. Hoffmann-La Roche Ltd sponsored atezolizu… Ended

2023-506184-34-00 Phase III 11 countries F. Hoffmann-La Roche AG

Showing 1–10 of 10 trials

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