234
Registered trials
87
Recruiting
91
Unique sponsors
170
Unique IMPs
199
Commercial trials
Drug classes (ATC)
—
ATC code not specified
125
L
Oncology (ATC L)
103
N
Neurology/Psychiatry (ATC N)
6
H
Endocrinology (ATC H)
2
B
Haematology (ATC B)
3
A
Gastroenterology (ATC A)
2
V
Various (ATC V)
1
Mechanism of action (INN-stem analysis)
Unknown / small molecule
78 substances
Kinase inhibitor
27 substances
Monoclonal antibody (immune)
11 substances
Antimetabolite
6 substances
Monoclonal antibody
5 substances
Antibody-drug conjugate (ADC)
5 substances
Monoclonal antibody (tumor, humanized)
3 substances
Taxane
3 substances
PARP inhibitor
3 substances
RAF/BRAF inhibitor
3 substances
Checkpoint inhibitor (PD-1)
2 substances
Checkpoint inhibitor (PD-L1)
2 substances
Checkpoint inhibitor (CTLA-4)
2 substances
Platinum compound
2 substances
Corticosteroid
2 substances
Vinca alkaloid
2 substances
Monoclonal antibody (immune, humanized)
2 substances
Monoclonal antibody (chimeric)
1 substance
Immunosuppressant
1 substance
Monoclonal antibody (human)
1 substance
Alkylating agent
1 substance
Statin
1 substance
Colony-stimulating factor
1 substance
BCL-2 inhibitor
1 substance
Monoclonal antibody (angiogenesis)
1 substance
Anthracycline
1 substance
SERD
1 substance
CDK inhibitor
1 substance
Supportive / diluent
1 substance
Phase III:
57
Phase II/III:
7
Phase II:
63
Phase I/II:
20
Phase IV:
5
Phase I:
37
Phase I (Other):
27
Phase I (First in Human):
19
Phase III
57 trials-
EndedAmgen Inc. CommercialIMP not specified
-
RecruitingAmgen Inc. CommercialROMIPLOSTIM
-
EndedAmgen Inc. CommercialDEXAMETHASONE
-
EndedArcus Biosciences Inc. CommercialDOMVANALIMAB; PEMBROLIZUMAB; ZIMBERELIMAB
-
RecruitingArrivent Biopharma Inc. CommercialN-[2-[2-(DIMETHYLAMINO)ETHYL-METHYLAMINO]-5-[[4-(1-METHYLINDOL-3-YL)PYRIMIDIN-2-YL]AMINO]-6-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-3-YL]PROP-2-ENAMIDE
-
RecruitingAstraZeneca AB CommercialDATOPOTAMAB DERUXTECAN; PEMBROLIZUMAB; RILVEGOSTOMIG
-
EndedAstraZeneca AB CommercialDURVALUMAB
-
EndedAstraZeneca AB CommercialDURVALUMAB
-
RecruitingAstraZeneca AB CommercialOSIMERTINIB
-
RecruitingBayer AG Commercial3-(3-CHLORO-2-METHOXYANILINO)-2-{3-[(2S)-1,4-DIOXAN-2-YLMETHOXY]PYRIDIN-4-YL}-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE; BAY 2927088; CARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; PEMETREXED; SEVABERTINIB
-
RecruitingBoehringer Ingelheim International GmbH CommercialCARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; PEMETREXED; ZONGERTINIB
-
RecruitingBoehringer Ingelheim International GmbH CommercialATEZOLIZUMAB; DURVALUMAB; NIVOLUMAB; PEMBROLIZUMAB; ZONGERTINIB
-
EndedBristol Myers Squibb International Corporation CommercialCARBOPLATIN; CISPLATIN; DOCETAXEL; GEMCITABINE; IPILIMUMAB; NIVOLUMAB; PACLITAXEL; PEMETREXED; VINORELBINE; VINORELBINE TARTRATE
-
EndedBristol-Myers Squibb Services Unlimited Company CommercialCARBOPLATIN; CISPLATIN; DOCETAXEL; NIVOLUMAB; PACLITAXEL; PEMETREXED
-
RecruitingBristol-Myers Squibb Services Unlimited Company CommercialCRIZOTINIB; REPOTRECTINIB
-
PendingBristol-Myers Squibb Services Unlimited Company CommercialPUMITAMIG
-
EndedDaiichi Sankyo Inc. CommercialDATOPOTAMAB DERUXTECAN; PEMBROLIZUMAB
-
EndedDaiichi Sankyo Inc. CommercialDATOPOTAMAB DERUXTECAN; PEMBROLIZUMAB
-
EndedDaiichi Sankyo Inc. CommercialDATOPOTAMAB DERUXTECAN
-
EndedF. Hoffmann-La Roche AG CommercialATEZOLIZUMAB; TIRAGOLUMAB
-
RecruitingF. Hoffmann-La Roche AG CommercialALECTINIB; DURVALUMAB
-
EndedF. Hoffmann-La Roche AG CommercialATEZOLIZUMAB; CARBOPLATIN; CISPLATIN; GEMCITABINE; PACLITAXEL ALBUMIN-BOUND; PEMETREXED
-
EndedF. Hoffmann-La Roche AG CommercialALECTINIB; ALECTINIB HYDROCHLORIDE; ATEZOLIZUMAB; CABOZANTINIB; COBIMETINIB; NIRAPARIB; PACLITAXEL; PEMETREXED; SUNITINIB; VEMURAFENIB; VENETOCLAX
-
EndedF. Hoffmann-La Roche AG CommercialATEZOLIZUMAB
-
EndedF. Hoffmann-La Roche AG CommercialIMP not specified
-
EndedF. Hoffmann-La Roche AG CommercialCRIZOTINIB; ENTRECTINIB
-
EndedF. Hoffmann-La Roche AG CommercialIMP not specified
-
EndedGilead Sciences Inc. CommercialDOCETAXEL; SACITUZUMAB GOVITECAN
-
EndedGlaxosmithkline Research & Development Limited CommercialNIRAPARIB TOSILATE MONOHYDRATE; PEMBROLIZUMAB
-
EndedJanssen - Cilag International CommercialAMIVANTAMAB; CARBOPLATIN; PEMETREXED
-
EndedJanssen - Cilag International CommercialAMIVANTAMAB; LAZERTINIB; OSIMERTINIB
-
EndedJanssen - Cilag International CommercialAMIVANTAMAB; LAZERTINIB
-
RecruitingMaia Biotechnology Inc. Commercial2-AMINO-9-((2R,4R,5R)-4-HYDROXY-5-(HYDROXYMETHYL) TETRAHYDROFURAN-2-YL)-1,4,5,9-TETRAHYDRO-6H-PURINE-6-THIONE; CEMIPLIMAB; DOCETAXEL; GEMCITABINE; VINORELBINE
-
EndedMerck Sharp & Dohme LLC CommercialPEMBROLIZUMAB
-
RecruitingMerck Sharp & Dohme LLC CommercialSACITUZUMAB TIRUMOTECAN
-
RecruitingMerck Sharp & Dohme LLC CommercialMRNA-4157; PEMBROLIZUMAB
-
RecruitingMerck Sharp & Dohme LLC CommercialMRNA-4157; PEMBROLIZUMAB
-
EndedMerck Sharp & Dohme LLC CommercialPEMBROLIZUMAB
-
EndedMirati Therapeutics Inc. CommercialADAGRASIB; DOCETAXEL
-
HaltedNovartis Pharma AG Commercial1-{6-[(4M)-4-(5-CHLORO-6-METHYL-1H -INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H -INDAZOL-5-YL)-1H -PYRAZOL-1-YL]-2-AZASPIRO[3.3]HEPTAN-2-YL}PROP-2-EN-1-ONE
-
EndedNovartis Pharma AG CommercialIMP not specified
-
RecruitingNuvalent Inc. CommercialALECTINIB HYDROCHLORIDE; NVL-655
-
EndedPfizer Inc. CommercialIMP not specified
-
RecruitingPfizer Inc. CommercialPEMBROLIZUMAB; SIGVOTATUG VEDOTIN
-
RecruitingPfizer Inc. CommercialHUMANISED IGG1 MONOCLONAL ANTIBODY AGAINST PD-L1 CONJUGATED TO MONOMETHYL AURISTATIN E VIA A VALINE-CITRULLINE LINKER
-
RecruitingQilu Pharmaceutical Co. Ltd. CommercialPEMBROLIZUMAB
-
EndedRegeneron Pharmaceuticals Inc. CommercialCARBOPLATIN; CEMIPLIMAB; CISPLATIN; IPILIMUMAB; PACLITAXEL; PEMETREXED
-
EndedRegeneron Pharmaceuticals Inc. CommercialCARBOPLATIN; CEMIPLIMAB; CISPLATIN; GEMCITABINE; PACLITAXEL; PEMETREXED
-
RecruitingRevolution Medicines Inc. Commercial(12M)-(1S,2S)-N-((63S,4S,Z)-11-ETHYL-12-(2-((S)-1-METHOXYETHYL)-5-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-3-YL)-10,10-DIMETHYL-5,7-DIOXO-61,62,63,64,65,66-HEXAHYDRO-11H-8-OXA-2(4,2)-THIAZOLA-1(5,3)-INDOLA-6(1,3)-PYRIDAZINACYCLOUNDECAPHANE-4-YL)-2-METHYLCYCLOPROPANE-1-CARBOXAMIDE
-
EndedSeagen Inc. CommercialSIGVOTATUG VEDOTIN
-
EndedTaiho Oncology Inc. CommercialCARBOPLATIN; CISPLATIN; PEMETREXED; ZIPALERTINIB
-
RecruitingTaiho Oncology Inc. CommercialCARBOPLATIN; CISPLATIN; PEMETREXED; ZIPALERTINIB
-
RecruitingAstraZeneca AB AcademicOSIMERTINIB
-
RecruitingETOP IBCSG Partners Foundation AcademicDURVALUMAB
-
RecruitingETOP IBCSG Partners Foundation AcademicCEMIPLIMAB
-
RecruitingFundacion GECP AcademicSACITUZUMAB GOVITECAN; ZIMBERELIMAB
-
RecruitingInstitut Gustave Roussy AcademicSODIUM CHLORIDE; TISLELIZUMAB
Phase II/III
7 trials-
RecruitingAbbVie Deutschland GmbH & Co. KG CommercialTELISOTUZUMAB ADIZUTECAN
-
RecruitingAbbVie Deutschland GmbH & Co. KG CommercialTELISOTUZUMAB ADIZUTECAN
-
PendingBristol-Myers Squibb Services Unlimited Company CommercialIZALONTAMAB BRENGITECAN
-
EndedGlaxosmithkline Research & Development Limited CommercialCOBOLIMAB; DOCETAXEL; DOSTARLIMAB
-
RecruitingMirati Therapeutics Inc. CommercialADAGRASIB; PEMBROLIZUMAB
-
EndedRegeneron Pharmaceuticals Inc. CommercialCEMIPLIMAB; FIANLIMAB
-
RecruitingEuropean Organisation For Research And Treatment Of Cancer AcademicIMP not specified
Phase II
63 trials-
EndedAbbVie Deutschland GmbH & Co. KG CommercialTELISOTUZUMAB VEDOTIN
-
RecruitingAmgen Inc. CommercialAMG 193
-
EndedAstraZeneca AB CommercialDURVALUMAB; INFLIXIMAB; MYCOPHENOLATE MOFETIL
-
EndedAstraZeneca AB CommercialDATOPOTAMAB DERUXTECAN; DURVALUMAB; INFLIXIMAB; MYCOPHENOLATE MOFETIL; OSIMERTINIB; SELUMETINIB
-
EndedAstraZeneca AB CommercialOSIMERTINIB
-
EndedAstraZeneca AB CommercialDURVALUMAB; OLAPARIB
-
PendingAstraZeneca AB CommercialRILVEGOSTOMIG
-
EndedBristol Myers Squibb International Corporation CommercialFARLETUZUMAB ECTERIBULIN
-
EndedCelgene Corp. CommercialAZACITIDINE
-
EndedDaiichi Sankyo Inc. CommercialDATOPOTAMAB DERUXTECAN
-
PendingDualitybio Inc. CommercialBNT324; BNT327; HUMANISED IGG1 MONOCLONAL ANTIBODY AGAINST TROP2 CONJUGATED TO N-((7S,15S)-7-BENZYL-17-(((1S,9S)-9-ETHYL-5-FLUORO-9-HYDROXY-4-METHYL-10,13-DIOXO-2,3,9,10,13,15-HEXAHYDRO-1H,12H-BENZO[DE]PYRANO[3',4':6,7] INDOLIZINO[1,2-B]QUINOLIN-1-YL)AMINO)-15-METHYL-2,5,8,11,17-PENTAOXO-14-OXA-3,6,9,12-TETRAAZAHEPTADECYL)-6-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)HEXANAMIDE
-
EndedF. Hoffmann-La Roche AG CommercialIMP not specified
-
RecruitingF. Hoffmann-La Roche AG CommercialALECTINIB; CARBOPLATIN; CISPLATIN; PEMETREXED
-
EndedGenentech Inc. CommercialATEZOLIZUMAB; TIRAGOLUMAB
-
EndedGenmab A/S CommercialACASUNLIMAB; PEMBROLIZUMAB
-
EndedGilead Sciences Inc. CommercialCARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; SACITUZUMAB GOVITECAN
-
EndedGlaxosmithkline Research & Development Limited CommercialCARBOPLATIN; CISPLATIN; DOSTARLIMAB; PEMBROLIZUMAB; PEMETREXED
-
EndedIncyte Corp. CommercialINCB099280
-
EndedIovance Biotherapeutics Inc. CommercialAUTOLOGOUS TUMOUR-INFILTRATING LYMPHOCYTES; CYCLOPHOSPHAMIDE; FLUDARABINE PHOSPHATE; LIFILEUCEL; PEMBROLIZUMAB
-
RecruitingJanssen - Cilag International CommercialAMIVANTAMAB; LAZERTINIB
-
EndedJanssen - Cilag International CommercialAMIVANTAMAB; DEXAMETHASONE; LAZERTINIB; METHOTREXATE; MONTELUKAST SODIUM
-
RecruitingJazz Pharmaceuticals Ireland Limited CommercialZANIDATAMAB
-
RecruitingJohnson & Johnson Enterprise Innovation Inc. CommercialHAFNIUM OXIDE
-
RecruitingMaia Biotechnology Inc. Commercial2-AMINO-9-((2R,4R,5R)-4-HYDROXY-5-(HYDROXYMETHYL) TETRAHYDROFURAN-2-YL)-1,4,5,9-TETRAHYDRO-6H-PURINE-6-THIONE; CEMIPLIMAB
-
EndedMerck Sharp & Dohme LLC CommercialPEMBROLIZUMAB
-
RecruitingMerus B.V. CommercialPEMBROLIZUMAB; PETOSEMTAMAB
-
EndedMirati Therapeutics Inc. CommercialADAGRASIB
-
RecruitingNovartis Pharma AG Commercial177LU-FAP-2286; CALCIUM FOLINATE; FAP-2286; PACLITAXEL ALBUMIN-BOUND
-
HaltedNovartis Pharma AG Commercial1-{6-[(4M)-4-(5-CHLORO-6-METHYL-1H -INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H -INDAZOL-5-YL)-1H -PYRAZOL-1-YL]-2-AZASPIRO[3.3]HEPTAN-2-YL}PROP-2-EN-1-ONE
-
EndedPfizer Inc. CommercialBINIMETINIB; ENCORAFENIB
-
RecruitingRegeneron Pharmaceuticals Inc. CommercialCEMIPLIMAB; ENOMIMERAN, RBL005.3, RBL007.2, RBL012.2, RBL027.2, RBL035.2
-
RecruitingRegeneron Pharmaceuticals Inc. CommercialCEMIPLIMAB; CEMIPLIMAB, FIANLIMAB
-
RecruitingRegeneron Pharmaceuticals Inc. CommercialCARBOPLATIN; CEMIPLIMAB; CISPLATIN; PACLITAXEL; PEMETREXED; REGN7075
-
RecruitingRevolution Medicines Inc. Commercial(12M)-(1S,2S)-N-((63S,4S,Z)-11-ETHYL-12-(2-((S)-1-METHOXYETHYL)-5-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-3-YL)-10,10-DIMETHYL-5,7-DIOXO-61,62,63,64,65,66-HEXAHYDRO-11H-8-OXA-2(4,2)-THIAZOLA-1(5,3)-INDOLA-6(1,3)-PYRIDAZINACYCLOUNDECAPHANE-4-YL)-2-METHYLCYCLOPROPANE-1-CARBOXAMIDE; (2S)-2-CYCLOPENTYL-2-[(5S)-2-[(2R,3R)-3-CYCLOPROPYL-1-METHYLAZIRIDINE-2-CARBONYL]-2,7-DIAZASPIRO[4.4]NONAN-7-YL]-N-[(6S,8S,14S)-21-[5-(4-CYCLOPROPYLPIPERAZIN-1-YL)-2-[(1S)-1-METHOXYETHYL]PYRIDIN-3-YL]-18,18-DIMETHYL-9,15-DIOXO-22-(2,2,2-TRIFLUOROETHYL)-5,16-DIOXA-2,10,22,28-TETRAZAPENTACYCLO[18.5.2.12,6.110,14.023,27]NONACOSA-1(26),20,23(27),24-TETRAEN-8-YL]ACETAMIDE
-
EndedRevolution Medicines Inc. Commercial(2S)-2-CYCLOPENTYL-2-[(5S)-2-[(2R,3R)-3-CYCLOPROPYL-1-METHYLAZIRIDINE-2-CARBONYL]-2,7-DIAZASPIRO[4.4]NONAN-7-YL]-N-[(6S,8S,14S)-21-[5-(4-CYCLOPROPYLPIPERAZIN-1-YL)-2-[(1S)-1-METHOXYETHYL]PYRIDIN-3-YL]-18,18-DIMETHYL-9,15-DIOXO-22-(2,2,2-TRIFLUOROETHYL)-5,16-DIOXA-2,10,22,28-TETRAZAPENTACYCLO[18.5.2.12,6.110,14.023,27]NONACOSA-1(26),20,23(27),24-TETRAEN-8-YL]ACETAMIDE
-
EndedSeagen Inc. CommercialPEMBROLIZUMAB; TISOTUMAB VEDOTIN
-
RecruitingSeagen Inc. CommercialDISITAMAB VEDOTIN
-
RecruitingShanghai Henlius Biotech Inc. CommercialHLX43
-
EndedSichuan Kelun-Biotech Biopharmaceutical Co. Ltd. CommercialSKB264
-
RecruitingSynthekine Inc. CommercialCARBOPLATIN; PEMBROLIZUMAB; PEMETREXED; STK-012
-
RecruitingTaiho Oncology Inc. CommercialDEXTROMETHORPHAN; DIGOXIN; MIDAZOLAM; ROSUVASTATIN; ZIPALERTINIB
-
RecruitingWayshine Biopharm Inc. Commercial(R)-6-((3,3-DIFLUORO-1-METHYLPIPERIDIN-4-YL)OXY)-N-(3-ETHYNYL-2-FLUOROPHENYL)-7-METHOXYQUINAZOLIN-4-AMINE-FUMARATE (2:1)
-
EndedAIO-Studien gGmbH AcademicOSIMERTINIB
-
PendingAIO-Studien gGmbH AcademicSACITUZUMAB GOVITECAN; ZIMBERELIMAB
-
EndedCentre Hospitalier Regional De Marseille AcademicCERALASERTIB; MONALIZUMAB; OLECLUMAB; SAVOLITINIB
-
EndedETOP IBCSG Partners Foundation AcademicADAGRASIB
-
EndedETOP IBCSG Partners Foundation AcademicDURVALUMAB; TREMELIMUMAB
-
EndedETOP IBCSG Partners Foundation AcademicAMIVANTAMAB; BEVACIZUMAB; LAZERTINIB
-
RecruitingFondazione Ricerca Traslazionale AcademicDACOMITINIB; OSIMERTINIB
-
PendingFondazione Ricerca Traslazionale AcademicCABOZANTINIB
-
RecruitingFondazione Ricerca Traslazionale AcademicCEMIPLIMAB; MPS-112, MPS-106, MPS-213, MPS-102, MPS-216, MPS-103, MPS-215, MPS-214, D-ALA-LYS-CHA-VAL-ALA-ALA-TRP-THR-LEU-LYS-ALA-ALA-D-ALA, MPS-200; PEMETREXED
-
PendingFondazione Ricerca Traslazionale AcademicAMIVANTAMAB; PEMETREXED
-
EndedFrankfurter Institut Fuer Klinische Krebsforschung IKF GmbH AcademicBRIGATINIB; CERITINIB
-
EndedFundacion GECP AcademicNIVOLUMAB
-
EndedFundacion GECP AcademicIPILIMUMAB; NIVOLUMAB
-
EndedFundacion GECP AcademicATEZOLIZUMAB
-
RecruitingFundacion GECP AcademicCARBOPLATIN; CEMIPLIMAB; PACLITAXEL; PEMETREXED
-
RecruitingFundacion GECP AcademicCARBOPLATIN; DURVALUMAB; PACLITAXEL; RIFAXIMIN
-
RecruitingInstitut Gustave Roussy AcademicIMP not specified
-
EndedInstitut Gustave Roussy AcademicSOTORASIB
-
RecruitingInstitut Gustave Roussy AcademicALLOGENEIC FAECAL MICROBIOTA, POOLED; CEMIPLIMAB
-
EndedUniversitaetsklinikum Essen AöR AcademicNIVOLUMAB; RELATLIMAB
-
EndedVestre Viken HF AcademicOSIMERTINIB
Phase I/II
20 trials-
RecruitingAbbVie Deutschland GmbH & Co. KG CommercialBUDIGALIMAB; CARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; PEMETREXED; TELISOTUZUMAB ADIZUTECAN
-
EndedAmgen Inc. CommercialAMG 193; IDE397
-
RecruitingApollomics Inc. CommercialAPL-101
-
EndedBergenbio ASA CommercialBEMCENTINIB
-
RecruitingBioNTech SE CommercialBNT326; BNT327
-
EndedBristol Myers Squibb International Corporation CommercialNIVOLUMAB
-
EndedBristol Myers Squibb International Corporation CommercialNIVOLUMAB; NIVOLUMAB, RELATLIMAB; RELATLIMAB
-
EndedCyclacel Limited CommercialCYC140 MONOHYDROCHLORIDE MONOHYDRATE
-
EndedEisai Limited CommercialFARLETUZUMAB ECTERIBULIN; LENVATINIB
-
RecruitingF. Hoffmann-La Roche AG CommercialBUDESONIDE; CARBOPLATIN; CISPLATIN; DIVARASIB; PEMBROLIZUMAB; PEMETREXED
-
EndedIncyte Corp. CommercialADAGRASIB; INCB099280
-
HaltedInstitut De Recherches Internationales Servier IRIS CommercialCEMIPLIMAB; SYM023; SYM024; SYM025
-
EndediOnctura SA CommercialANHYDROUS DOCETAXEL; DOSTARLIMAB; ROGINOLISIB
-
EndedJanssen - Cilag International CommercialAMIVANTAMAB; CAPMATINIB
-
RecruitingNovartis Pharma AG Commercial1-{6-[(4M)-4-(5-CHLORO-6-METHYL-1H -INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H -INDAZOL-5-YL)-1H -PYRAZOL-1-YL]-2-AZASPIRO[3.3]HEPTAN-2-YL}PROP-2-EN-1-ONE; RIBOCICLIB; TRAMETINIB; TRAMETINIB DIMETHYL SULFOXIDE
-
RecruitingRevolution Medicines Inc. CommercialIMP not specified
-
EndedVerastem Inc. CommercialAVUTOMETINIB; DEFACTINIB; SOTORASIB
-
EndedXencor Inc. CommercialCARBOPLATIN; PEMBROLIZUMAB; PEMETREXED; VUDALIMAB
-
RecruitingAmsterdam UMC Stichting AcademicSODIUM CHLORIDE; TREMELIMUMAB
-
RecruitingInstituto Portugues De Oncologia Do Porto Francisco Gentil E.P.E. AcademicDURVALUMAB
Phase IV
5 trials-
RecruitingNovartis Pharma AG CommercialDABRAFENIB MESYLATE; TRAMETINIB
-
EndedNovartis Pharma AG CommercialIMP not specified
-
EndedPfizer Inc. CommercialIMP not specified
-
EndedRazor Genomics Inc. CommercialIMP not specified
-
EndedAmphia Hospital AcademicCALCIUM FOLINATE
Phase I
37 trials-
RecruitingAbbVie Deutschland GmbH & Co. KG CommercialIMP not specified
-
EndedAmgen Inc. CommercialIMP not specified
-
RecruitingAmgen Inc. CommercialIMP not specified
-
EndedAstraZeneca AB CommercialIMP not specified
-
EndedBayer AG CommercialIMP not specified
-
EndedBeigene Ltd. CommercialIMP not specified
-
EndedBeigene Ltd. CommercialIMP not specified
-
RecruitingBeOne Medicines AG CommercialIMP not specified
-
EndedBeOne Medicines AG CommercialIMP not specified
-
RecruitingBioNTech Cell & Gene Therapies GmbH CommercialCLDN6 CAR-T; CLDN6 CAR-T(A); CLDN6 RNA-LPX; RBP030.2
-
EndedCullinan Therapeutics Inc. CommercialIMP not specified
-
EndedFusion Pharmaceuticals Inc. CommercialIMP not specified
-
RecruitingImmunocore Limited CommercialIMP not specified
-
RecruitingJanssen - Cilag International CommercialIMP not specified
-
RecruitingKura Oncology Inc. CommercialIMP not specified
-
PendingMerck Healthcare KGaA CommercialIMP not specified
-
EndedNovartis Pharma AG CommercialIMP not specified
-
EndedNovartis Pharma AG CommercialIMP not specified
-
RecruitingNovartis Pharma AG CommercialIMP not specified
-
EndedNovartis Pharma AG CommercialIMP not specified
-
RecruitingNovartis Pharma AG CommercialIMP not specified
-
EndedNykode Therapeutics ASA CommercialIMP not specified
-
RecruitingOne-carbon Therapeutics AB CommercialIMP not specified
-
RecruitingOnward Therapeutics France CommercialIMP not specified
-
EndedPfizer Inc. CommercialIMP not specified
-
EndedPfizer Inc. CommercialIMP not specified
-
EndedSeagen Inc. CommercialSGN-ALPV
-
EndedSeagen Inc. CommercialIMP not specified
-
HaltedSeagen Inc. CommercialIMP not specified
-
RecruitingSeagen Inc. CommercialIMP not specified
-
RecruitingSeagen Inc. CommercialIMP not specified
-
RecruitingTheras Inc. CommercialIMP not specified
-
EndedValo Therapeutics Oy CommercialIMP not specified
-
RecruitingZymeworks Inc. CommercialIMP not specified
-
EndedIncyte Corp. AcademicIMP not specified
-
RecruitingKarolinska University Hospital AcademicIMP not specified
-
EndedNovartis Pharma AG AcademicIMP not specified
Phase I (Other)
27 trials-
EndedADC Therapeutics S.A. CommercialIMP not specified
-
EndedAmgen Inc. CommercialIMP not specified
-
EndedAmgen Inc. CommercialIMP not specified
-
RecruitingArrivent Biopharma Inc. CommercialIMP not specified
-
RecruitingAstellas Pharma Global Development Inc. CommercialIMP not specified
-
EndedAstraZeneca AB CommercialDATOPOTAMAB DERUXTECAN; DURVALUMAB; RILVEGOSTOMIG; SABESTOMIG; VOLRUSTOMIG
-
RecruitingAstraZeneca AB CommercialCERALASERTIB; DURVALUMAB; DURVALUMAB, HYALURONIDASE (HUMAN RECOMBINANT); TREMELIMUMAB
-
EndedBayer AG CommercialIMP not specified
-
EndedBristol-Myers Squibb Services Unlimited Company CommercialIMP not specified
-
EndedDaiichi Sankyo Inc. CommercialIMP not specified
-
EndedDaiichi Sankyo Inc. CommercialIMP not specified
-
EndedDaiichi Sankyo Inc. CommercialIMP not specified
-
EndedExelixis Inc. CommercialIMP not specified
-
EndedGalecto Biotech AB Commercial2-(5-BROMOPYRIDIN-3-YL)SULFANYL-6-(HYDROXYMETHYL)-4-[4-(3,4,5-TRIFLUOROPHENYL)TRIAZOL-1-YL]OXANE-3,5-DIOL; 5-BROMOPYRIDIN-3-YL 3-DEOXY-1-THIO-3-[4-(3,4,5-TRIFLUOROPHENYL)-1H-1,2,3-TRIAZOL-1-YL]-ALFA-D-GALACTOPYRANOSIDE
-
EndedJanssen - Cilag International CommercialIMP not specified
-
EndedJiangsu Hansoh Pharmaceutical Group Co. Ltd. CommercialIMP not specified
-
EndedNovartis Pharma AG CommercialIMP not specified
-
EndedNovartis Pharma AG CommercialIMP not specified
-
EndedPfizer Inc. CommercialIMP not specified
-
RecruitingRevolution Medicines Inc. Commercial(12M)-(1S,2S)-N-((63S,4S,Z)-11-ETHYL-12-(2-((S)-1-METHOXYETHYL)-5-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-3-YL)-10,10-DIMETHYL-5,7-DIOXO-61,62,63,64,65,66-HEXAHYDRO-11H-8-OXA-2(4,2)-THIAZOLA-1(5,3)-INDOLA-6(1,3)-PYRIDAZINACYCLOUNDECAPHANE-4-YL)-2-METHYLCYCLOPROPANE-1-CARBOXAMIDE; CARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; PEMETREXED; RMC-6291
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RecruitingRevolution Medicines Inc. Commercial(12M)-(1S,2S)-N-((63S,4S,Z)-11-ETHYL-12-(2-((S)-1-METHOXYETHYL)-5-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-3-YL)-10,10-DIMETHYL-5,7-DIOXO-61,62,63,64,65,66-HEXAHYDRO-11H-8-OXA-2(4,2)-THIAZOLA-1(5,3)-INDOLA-6(1,3)-PYRIDAZINACYCLOUNDECAPHANE-4-YL)-2-METHYLCYCLOPROPANE-1-CARBOXAMIDE; CARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; PEMETREXED
-
RecruitingSystimmune Inc. CommercialIMP not specified
-
EndedTaiho Oncology Inc. Commercial[14C]ZIPALERTINIB
-
RecruitingUSWM Ct LLC CommercialLETETRESGENE AUTOLEUCEL
-
EndedFrankfurter Institut Fuer Klinische Krebsforschung IKF GmbH AcademicIMP not specified
-
PendingKarolinska University Hospital AcademicIMP not specified
-
EndedBayer AG AcademicIMP not specified
Phase I (First in Human)
19 trials-
EndedAmgen Inc. CommercialAMG 193
-
EndedAmgen Inc. CommercialIMP not specified
-
RecruitingBayer AG CommercialIMP not specified
-
EndedBeigene Ltd. CommercialLBL-007; SURZEBICLIMAB; TISLELIZUMAB
-
EndedBioNTech SE CommercialBNT142
-
EndedBristol-Myers Squibb Services Unlimited Company CommercialBMS-986442; NIVOLUMAB
-
PendingCrescent Biopharma Inc. CommercialCR-001
-
RecruitingDaiichi Sankyo Inc. CommercialDS-3939A
-
EndedDeciphera Pharmaceuticals Inc. CommercialDCC-3116; SOTORASIB
-
EndedEverimmune CommercialAKKERMANSIA MUCINIPHILA, STRAIN P2261, LIVE; ATEZOLIZUMAB; CEMIPLIMAB; IPILIMUMAB; NIVOLUMAB; PEMBROLIZUMAB
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RecruitingExscientia AI Limited CommercialBEVACIZUMAB; CAPECITABINE; DOXORUBICIN HYDROCHLORIDE; FULVESTRANT; GTAEXS617; PACLITAXEL
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EndedLoxo Oncology Inc. CommercialIMP not specified
-
EndedMythic Therapeutics Inc. CommercialIMP not specified
-
EndedNovartis Pharma AG Commercial1-{6-[(4M)-4-(5-CHLORO-6-METHYL-1H -INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H -INDAZOL-5-YL)-1H -PYRAZOL-1-YL]-2-AZASPIRO[3.3]HEPTAN-2-YL}PROP-2-EN-1-ONE; BATOPROTAFIB; TISLELIZUMAB
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EndedPDC line pharma CommercialALLOGENEIC PLASMACYTOID DENDRITIC CELLS, LOADED WITH SEVEN LUNG TUMOR ANTIGEN-DERIVED PEPTIDES, IRRADIATED; PEMBROLIZUMAB; PEMETREXED
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EndedRegeneron Pharmaceuticals Inc. CommercialDAVUTAMIG
-
EndedSalubris Biotherapeutics Inc. CommercialJK08; LENVATINIB; PEMBROLIZUMAB
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RecruitingSalubris Biotherapeutics Inc. CommercialJK06
-
EndedTaiho Oncology Inc. CommercialTAS3351
Sponsor activity
| Sponsor | Type | Trials | Phases | Recruiting |
|---|---|---|---|---|
| Novartis Pharma AG | Commercial | 16 | Phase I, Phase I (Other), Phase II, Phase III, Phase IV, Phase I (First in Human), Phase I/II | 5 |
| AstraZeneca AB | Commercial | 13 | Phase I, Phase I (Other), Phase II, Phase III | 4 |
| Amgen Inc. | Commercial | 11 | Phase I, Phase I (Other), Phase II, Phase III, Phase I (First in Human), Phase I/II | 3 |
| F. Hoffmann-La Roche AG | Commercial | 11 | Phase II, Phase III, Phase I/II | 3 |
| Janssen - Cilag International | Commercial | 8 | Phase I, Phase I (Other), Phase II, Phase III, Phase I/II | 2 |
| Pfizer Inc. | Commercial | 8 | Phase I, Phase I (Other), Phase II, Phase III, Phase IV | 2 |
| Seagen Inc. | Commercial | 8 | Phase I, Phase II, Phase III | 3 |
| Daiichi Sankyo Inc. | Commercial | 8 | Phase I (Other), Phase II, Phase III, Phase I (First in Human) | 1 |
| Regeneron Pharmaceuticals Inc. | Commercial | 7 | Phase II/III, Phase II, Phase III, Phase I (First in Human) | 3 |
| Bristol-Myers Squibb Services Unlimited Company | Commercial | 6 | Phase II/III, Phase I (Other), Phase III, Phase I (First in Human) | 1 |
| Revolution Medicines Inc. | Commercial | 6 | Phase I (Other), Phase II, Phase III, Phase I/II | 5 |
| Merck Sharp & Dohme LLC | Commercial | 6 | Phase II, Phase III | 3 |
| Fundacion GECP | Academic | 6 | Phase II, Phase III | 3 |
| AbbVie Deutschland GmbH & Co. KG | Commercial | 5 | Phase I, Phase II/III, Phase II, Phase I/II | 4 |
| Bayer AG | Commercial | 5 | Phase I, Phase I (Other), Phase III, Phase I (First in Human) | 2 |
| Taiho Oncology Inc. | Commercial | 5 | Phase I (Other), Phase II, Phase III, Phase I (First in Human) | 2 |
| ETOP IBCSG Partners Foundation | Academic | 5 | Phase II, Phase III | 2 |
| Bristol Myers Squibb International Corporation | Commercial | 4 | Phase II, Phase III, Phase I/II | 0 |
| Fondazione Ricerca Traslazionale | Academic | 4 | Phase II | 2 |
| Institut Gustave Roussy | Academic | 4 | Phase II, Phase III | 3 |
New trials by year
2019
13
2020
19
2021
13
2022
24
2023
33
2024
39
2025
48
2026
13