Oxaliplatin

• A Phase IIIb, Single Arm, Open-label, Multicentre Study of Durvalumab in Combination with Chemotherapy for the First Line Treatment for Pati… Not authorised
  2022-502043-35-00 Phase III 4 countries AstraZeneca AB
• Safety, tolerability, and efficacy of mFOLFIRINOX ±BNT321 as adjuvant therapy following curative resection in patients with pancreatic adeno… Not authorised
  2023-506014-47-00 Phase I/II 4 countries BioNTech SE
• Perioperative versus adjuvant FOLFIRINOX for resectable pancreatic cancer: the PREOPANC-3 study Pending
  2024-510617-15-00 Phase III 2 countries Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
• Neo-adjuvant intraperitoneal chemotherapy (irinotecan) and systemic chemotherapy (mFOLFOX4-bevacizumab) prior to CRS-HIPEC for patients with… Pending
  2024-512318-16-00 Phase II 1 country Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
• A study to evaluate the efficacy of oxaliplatin- or gemcitabine-based chemotherapy after allocation by standard criteria or by genetic marke… Pending
  2024-514682-19-00 Phase III 2 countries Universitaetsklinikum Heidelberg AöR
• TOTAL NEOADJUVANT TREATMENT WITHOUT SURGERY FOR LOCALLY ADVANCED RECTAL CANCER: PROSPECTIVE CLINICAL TRIAL TO ASSESS TUMOR COMPLETE RESPONSE… Pending
  2024-515225-28-00 Phase II/III 1 country ASST Grande Ospedale Metropolitano Niguarda
• Phase II study of Durvalumab (MEDI4736) plus Total Neoadjuvant Therapy (TNT) in locally advanced rectal cancer (The DUREC trial) Pending
  2024-515240-24-00 Phase II 1 country Grupo Espanol Multidisciplinar En Cancer Digestivo
• Systemic Neoadjuvant and adjuvant Control by Precision medicine in rectal cancer (SYNCOPE) – approach on high-risk group to reduce metastase… Pending
  2024-517149-15-00 Phase IV 1 country HUS-Yhtymae
• Randomized trial of standard chemotherapy alone or combined with atezolizumab as adjuvant therapy for patients with stage III colon cancer a… Pending
  2024-517269-18-00 Phase III 1 country AIO-Studien gGmbH; National Cancer Institute
• BALLAD Belgium - A trial to evaluate the potential benefit of adjuvant chemotherapy for small bowel adenocarcinoma. The Belgian component of… Pending
  2024-518349-85-01 Phase III 1 country Groupe Belge D'Oncologie Digestive
• Chemo-immunotherapy before and after surgery for peritoneal metastases of large bowel cancer. Pending
  2024-518570-13-00 Phase II/III 2 countries Catharina Ziekenhuis Stichting
• A randomized phase III trial of short-course versus long-course pre-operative chemotherapy with mFOLFIRINOX or PAXG regimen for stage I-III … Pending
  2024-519031-42-00 Phase III 1 country Associazione Italiana Per Lo Studio Del Pancreas
• PRODIGE 104 – NEOPREDICT A multicenter phase II trial using transcriptomic signatures to personalize neoadjuvant chemotherapy for patients … Pending
  2024-519753-11-00 Phase II 1 country Fondation Franc.Cancerologie Digestive
• Efficacy of the use of neoadjuvant with/without hyperthermic intraperitoneal chemotherapy in the treatment of locally advanced colon cancer Pending
  2025-520471-29-00 Phase III 1 country Fundacion Para La Investigacion Biomedica De Cordoba
• Personalizing chemotherapy selection after surgery for patients with stage III colorectal cancer using a blood test Pending
  2025-521045-24-00 Phase III 2 countries Unicancer
• A biomarker enrichment trial of anti-EGFR agents in patients with advanced colorectal cancer (aCRC) with wild-type RAS and right primary tum… Pending
  2025-521209-42-00 Phase IV 3 countries Fondazione GONO G.I.
• A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with FOLFOX versus Bevacizu… Pending
  2025-521587-35-00 Phase III 8 countries Summit Therapeutics Inc.
• Study evaluating two treatment strategies for rectal cancer in patients ≥75 years old Pending
  2025-521619-37-00 Phase III 1 country Unicancer
• Molecularly Tailored Therapy versus Standard Care in Advanced Pancreatic Cancer Pending
  2025-522431-34-00 Phase II 1 country Region Hovedstaden
• A phase 2, single arm, open label, study on the safety and feasibility of Liver Isolated Oxaliplatin (LIOX) delivered via arterial access de… Pending
  2025-523261-25-00 Phase II 1 country UZ Leuven
• A Study of S241656 in Patients With KRAS, BRAF and Other Selected RAS/MAPK Mutation-Positive Malignancies Pending
  2025-523474-16-00 Phase I (FiH) 4 countries Institut De Recherches Internationales Servier IRIS
• A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorect… Pending
  2025-523521-18-00 Phase III 8 countries Pfizer Inc.
• A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treat… Pending
  2025-523735-19-00 Phase III 10 countries Incyte Corp.
• LuMIERE: A Phase 1/2, Multicenter, Open label, Non randomized Study to Investigate Safety and Tolerability, Pharmacokinetics, Dosimetry, and… Recruiting
  2023-508995-12-01 Phase II 4 countries Novartis Pharma AG

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