Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC) — Sponsor Intelligence | 94 EU Trials

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94 Registered trials

46 Recruiting

17 Completed trials

14 Countries active

123 Unique IMPs

100% Results reported

Phase III

Phase II

Phase IV

Phase III: 15 Phase II/III: 3 Phase II: 17 Phase I/II: 7 Phase III/IV: 8 Phase IV: 27 Phase I: 3 Phase I (Other): 8 Phase I (FiH): 4 Other: 2

Oversight events:

2 serious breaches 1 temporary halt across 3 trials

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100%

17 of 17 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Glioblastoma multiforme 2 Rheumatoid arthritis 1 Cancer pain 1 Laser speckle contrast imaging 1 Prostate cancer metastatic 1 Complex regional pain syndrome 1 Oxytocin 1 Trigeminal nerve disorder 1 Cardiac sarcoidosis 1 Migraine 1

Top IMPs

IRINOTECAN HYDROCHLORIDE TRIHYDRATE 5 FLUOROURACIL 4 FOLINIC ACID 4 OXALIPLATIN 4 NIVOLUMAB 3 PEMBROLIZUMAB 3 (S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHYLCARBAMOYL)-QUINOLIN-6-YL)(METHYL)AMINO)-PROPYL)PIPERAZIN-1-YL)-2-OXOETHYL)-68GA-[1,4,7,10]-TETRAAZACYCLODODECANE-1,4,7-TRIYL)TRIACETATE 2 [AL[18F]F]FAPI-74 2 ALGLUCOSIDASE ALFA 2 AMOXICILLIN 2 AUTOLOGOUS DENDRITIC CELLS LOADED WITH ALLOGENIC ALLOGENEIC LYSATE OF MESOTHELIOMA CELL LINES 2 AVALGLUCOSIDASE ALFA 2

All trials

94 total

Increasing the dosing interval of osimertinib in patients with EGFR mutated locally advanced or meta-static non-small cell lung cancer - OSI… Not authorised

2024-514693-47-00 Phase III/IV 1 country OSIMERTINIB
Oxytocine and migraine Pending

2023-504690-21-00 Phase I (Other) 1 country
The ALPINE trial: a phase 1-2 study of intra-arterial [177Lu]Lu-PSMA-I&T for progressive or recurrent intracranial adult type diffuse gliom… Pending

2023-504696-24-00 Phase I (FiH) 2 countries
Iron Infusion in Elderly Patients undergoing Transcatheter Aortic Valve Implantation (IRON TAVI) Trial Pending

2023-505095-29-03 Phase IV 1 country FERRIC CARBOXYMALTOSE
A Phase II single arm open label study of Pembrolizumab and Lenvatinib in patients with high risk locally advanced cervix cancer: an EMBRACE… Pending

2023-506982-73-00 Phase II 1 country PEMBROLIZUMAB
Optimizing subcutaneous FEntanyl titRation: RApid achievement of adequate exposure when treating cancer-Related paIn (FERRARI-study). Pending

2023-507355-30-00 Phase IV 1 country
Perioperative versus adjuvant FOLFIRINOX for resectable pancreatic cancer: the PREOPANC-3 study Pending

2024-510617-15-00 Phase III 2 countries FLUOROURACIL; FOLINIC ACID; IRINOTECAN HYDROCHLORIDE TRIHYDRATE; OXALIPLATIN
Statins to Prevent Immune checkpoint inhibitor-induced pRogression of AtheroscLerosis Pending

2024-511127-33-00 Phase IV 1 country
Personalized tacrolimus treatment for pediatric kidney transplant recipients by using a dosing algorithm and a once-daily tacrolimus formula… Pending

2024-511585-36-00 Phase IV 1 country TACROLIMUS
Neo-adjuvant intraperitoneal chemotherapy (irinotecan) and systemic chemotherapy (mFOLFOX4-bevacizumab) prior to CRS-HIPEC for patients with… Pending

2024-512318-16-00 Phase II 1 country BEVACIZUMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN HYDROCHLORIDE TRIHYDRATE; OX…
COATS (genetic Clopidogrel response testing to finetune the antithrombotic regimen in (D)OAC Treated patients undergoing PCI) Study Pending

2024-512350-17-01 Phase IV 1 country CLOPIDOGREL; TICAGRELOR
Guided by Light: Optimizing Surgical Excision of Oral Cancer Using Realtime Fluorescence Imaging Pending

2024-512824-13-01 Phase I (FiH) 1 country CRGD-ZW800-1
Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk sco… Pending

2024-512850-10-00 Phase III 1 country
Avelumab Short Maintenance Trial Pending

2024-512975-11-01 Phase III/IV 1 country AVELUMAB
TACmono LT Pending

2024-513394-42-01 Phase III/IV 1 country PNEUMOCOCCAL POLYSACCHARIDE SEROTYPE 4, PNEUMOCOCCAL POLYSACCHARIDE SEROTYPE 6B,…
Differences in coagulation between fresh frozen plasma and Solvent-detergent plasma in pediatric congenital heart surgery. Pending

2024-514073-22-01 Phase III 1 country HUMAN PLASMA PROTEIN
Trametinib in neurofibromatosis type 1 related symptomatic plexiform neurofibromas Pending

2024-516593-30-00 Phase II 1 country TRAMETINIB
Nivolumab dose optimization in patients with a complete, partial or stable response (NIVOPTIMIZE-trial) Pending

2024-516718-39-00 Phase IV 1 country
Effects and health economic aspects of enzyme therapy in children and adults with Pompe disease Pending

2024-518269-92-00 Phase IV 1 country ALGLUCOSIDASE ALFA
The FIND study Pending

2024-518908-46-00 Phase III 1 country FLUOROETHYLTYROSINE F-18
IMMUNOPEC: Combination of neo-adjuvant Checkpoint Inhibition and Dendritic Cell Therapy (MesoPher) with Cytoreductive Surgery and Hypertherm… Pending

2024-519626-21-00 Phase II 1 country AUTOLOGOUS DENDRITIC CELLS LOADED WITH ALLOGENIC ALLOGENEIC LYSATE OF MESOTHELIO…
The use of [68Ga]Ga-FAPI PET/MRI in assessing disease activity in patients with Graves’ orbitopathy Pending

2025-521163-12-01 Phase I/II 1 country (S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHY…
ENDO-67 project: Investigating ENDOcrine therapy-related questions using Ki67 changes in the window-of-opportunity before breast surgery Pending

2025-521385-10-00 Phase IV 1 country
LOTUS Pending

2025-522111-42-02 Phase IV 1 country

Showing 1–24 of 94 trials

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