Spironolactone — Drug Intelligence | 9 EU Trials

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9 Registered trials

7 Recruiting

2 Completed trials

9 Sponsors

8 Countries

Phase III

Phase II

Phase III/IV

Phase IV

Phase III: 1 Phase II: 3 Phase III/IV: 1 Phase IV: 4

Indications tested

Aortic stenosis 1 Chronic kidney disease 1 Arrhythmogenic right ventricular dysplasia 1

Sponsors using this IMP

Bispebjerg Hospital 1 Fakultni Nemocnice Ostrava 1 Hospices Civils De Lyon 1 Les Hopitaux Universitaires De Strasbourg 1 Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy 1 Policlinico San Donato S.p.A. 1 Universitaetsmedizin Goettingen 1 Universitair Medisch Centrum Groningen 1 Ziekenhuis Oost Limburg 1

All trials

9 total

Pharmacological optimization in prevention in Heart Failure: A Sex-gap? Recruiting

2025-520660-18-00 Phase IV 1 country Policlinico San Donato S.p.A.
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS) Recruiting

2025-523743-35-00 Phase II 1 country Universitair Medisch Centrum Groningen
A trial investigating partial withdrawal of heart failure therapy in patients with heart failure in remission. Recruiting

2025-522560-32-01 Phase IV 1 country Ziekenhuis Oost Limburg
BLOCKADE OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN PATIENTS WITH ARVD.BRAVE Recruiting

2023-505048-20-00 Phase II 1 country Hospices Civils De Lyon
Use of determination of drug levels to optimize pharmacotherapy of heart failure Recruiting

2023-506283-13-00 Phase IV 1 country Fakultni Nemocnice Ostrava
Optimal medical treatment of difficult-to-treat hypertension. Recruiting

2024-517628-20-00 Phase III/IV 1 country Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut …
CROWD-ASPECT Recruiting

2022-502239-20-00 Phase IV 1 country Bispebjerg Hospital
A MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF SPIRONOLACTONE FOR THE TREATMENT OF ACTIVE RHEUMATOID ARTH… Ended

2024-516884-10-00 Phase III 2 countries Les Hopitaux Universitaires De Strasbourg
Effect of antifibrotic therapy on regression of myocardial fibrosis after transcatheter aortic valve implantation (TAVI) in aortic stenosis … Ended

2024-510869-42-00 Phase II 1 country Universitaetsmedizin Goettingen

Showing 1–9 of 9 trials

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