29
Registered trials
10
Recruiting
22
Unique sponsors
42
Unique IMPs
22
Commercial trials
Drug classes (ATC)
—
ATC code not specified
14
L
Oncology (ATC L)
14
B
Haematology (ATC B)
1
V
Various (ATC V)
2
Mechanism of action (INN-stem analysis)
Unknown / small molecule
14 substances
Monoclonal antibody (immune)
4 substances
Antimetabolite
3 substances
Antibody-drug conjugate (ADC)
3 substances
Checkpoint inhibitor (PD-L1)
2 substances
Kinase inhibitor
2 substances
Checkpoint inhibitor (CTLA-4)
2 substances
Platinum compound
2 substances
Macrolide / aminoglycoside
2 substances
Alkylating agent
2 substances
Checkpoint inhibitor (PD-1)
1 substance
Supportive / diluent
1 substance
Monoclonal antibody (unknown source)
1 substance
Monoclonal antibody (tumor, humanized)
1 substance
PARP inhibitor
1 substance
Topoisomerase II inhibitor
1 substance
Phase III:
8
Phase II:
8
Phase I/II:
3
Phase IV:
2
Phase I:
3
Phase I (Other):
2
Phase I (First in Human):
3
Phase III
8 trials-
EndedAstraZeneca AB CommercialDURVALUMAB; TREMELIMUMAB
-
EndedBristol-Myers Squibb Services Unlimited Company CommercialCISPLATIN; GEMCITABINE HYDROCHLORIDE; NIVOLUMAB
-
EndedJanssen - Cilag International CommercialGEMCITABINE HYDROCHLORIDE
-
RecruitingMerck Sharp & Dohme LLC CommercialSACITUZUMAB TIRUMOTECAN
-
EndedUrogen Pharma Ltd. CommercialMITOMYCIN
-
EndedUrogen Pharma Ltd. CommercialPOLOXAMER 407
-
EndedUnicancer AcademicIMP not specified
-
PendingUnicancer AcademicATEZOLIZUMAB
Phase II
8 trials-
PendingAstraZeneca AB CommercialDURVALUMAB
-
RecruitingBayer Consumer Care AG Commercial3-(3-CHLORO-2-METHOXYANILINO)-2-{3-[(2S)-1,4-DIOXAN-2-YLMETHOXY]PYRIDIN-4-YL}-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE; BAY 2927088; SEVABERTINIB
-
EndedBoehringer Ingelheim International GmbH Commercial(3S,3'S,3A'S,10A'S)-6-CHLORO-3'-(3-CHLORO-2-FLUOROPHENYL)-1'-(CYCLOPROPYLMETHYL)-6'-METHYL-2-OXO-1,2,3',3A',10',10A'-HEXAHYDRO-1'H-SPIRO[INDOLE-3,2'-PYRROLO[2',3':4,5]PYRROLO[1,2-B]INDAZOLE]-7'-CARBOXYLIC ACID
-
EndedCatalYm GmbH CommercialNIVOLUMAB; SODIUM CHLORIDE; VISUGROMAB
-
RecruitingMerck Sharp & Dohme LLC CommercialMRNA-4157
-
EndedAssociacio Per A La Recerca Oncologica AcademicANTI-PDCD1 IGG4 HUMANISED MONOCLONAL ANTIBODY; SACITUZUMAB GOVITECAN; SASANLIMAB
-
PendingFondazione IRCCS Istituto Nazionale Dei Tumori AcademicSACITUZUMAB GOVITECAN; ZIMBERELIMAB
-
EndedGrupo Espanol De Oncologia Genitourinaria-Socug AcademicCETRELIMAB; ERDAFITINIB
Phase I/II
3 trials-
EndedBristol Myers Squibb International Corporation CommercialNIVOLUMAB; NIVOLUMAB, RELATLIMAB; RELATLIMAB
-
EndedBristol Myers Squibb International Corporation CommercialIPILIMUMAB; NIVOLUMAB
-
EndedCyclacel Limited CommercialCYC140 MONOHYDROCHLORIDE MONOHYDRATE
Phase IV
2 trials-
PendingAzienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino AcademicHEXAMINOLEVULINATE
-
RecruitingTurku University Hospital AcademicBLEOMYCIN SULFATE PH. EUR.; CAPECITABINE; CISPLATIN; ETOPOSIDE; GEMCITABINE; IFOSFAMIDE; MESNA; OXALIPLATIN
Phase I
3 trials-
RecruitingBeOne Medicines AG CommercialIMP not specified
-
RecruitingMerck Sharp & Dohme LLC CommercialIMP not specified
-
RecruitingSeagen Inc. CommercialIMP not specified
Phase I (Other)
2 trials-
EndedExelixis Inc. CommercialIMP not specified
-
EndedToray Industries Inc. CommercialIMP not specified
Phase I (First in Human)
3 trials-
RecruitingAstraZeneca AB Commercial[11C]AZ14193391; 6-FLUORO-5-[4-[(5-FLUORO-2-METHYL-3-OXO-4H-QUINOXALIN-6-YL)METHYL]PIPERAZIN-1-YL]-N-METHYLPYRIDINE-2-CARBOXAMIDE; DATOPOTAMAB DERUXTECAN; PALACAPARIB; TEMOZOLOMIDE; TRASTUZUMAB DERUXTECAN
-
RecruitingEngene Inc. CommercialDETALIMOGENE VORAPLASMID
-
RecruitingSalubris Biotherapeutics Inc. CommercialJK06
Sponsor activity
| Sponsor | Type | Trials | Phases | Recruiting |
|---|---|---|---|---|
| Merck Sharp & Dohme LLC | Commercial | 3 | Phase I, Phase II, Phase III | 3 |
| AstraZeneca AB | Commercial | 3 | Phase II, Phase III, Phase I (First in Human) | 1 |
| Urogen Pharma Ltd. | Commercial | 2 | Phase III | 0 |
| Bristol Myers Squibb International Corporation | Commercial | 2 | Phase I/II | 0 |
| Unicancer | Academic | 2 | Phase III | 0 |
| BeOne Medicines AG | Commercial | 1 | Phase I | 1 |
| Seagen Inc. | Commercial | 1 | Phase I | 1 |
| Exelixis Inc. | Commercial | 1 | Phase I (Other) | 0 |
| Toray Industries Inc. | Commercial | 1 | Phase I (Other) | 0 |
| Bayer Consumer Care AG | Commercial | 1 | Phase II | 1 |
| Boehringer Ingelheim International GmbH | Commercial | 1 | Phase II | 0 |
| CatalYm GmbH | Commercial | 1 | Phase II | 0 |
| Bristol-Myers Squibb Services Unlimited Company | Commercial | 1 | Phase III | 0 |
| Janssen - Cilag International | Commercial | 1 | Phase III | 0 |
| Engene Inc. | Commercial | 1 | Phase I (First in Human) | 1 |
| Salubris Biotherapeutics Inc. | Commercial | 1 | Phase I (First in Human) | 1 |
| Cyclacel Limited | Commercial | 1 | Phase I/II | 0 |
| Associacio Per A La Recerca Oncologica | Academic | 1 | Phase II | 0 |
| Fondazione IRCCS Istituto Nazionale Dei Tumori | Academic | 1 | Phase II | 0 |
| Grupo Espanol De Oncologia Genitourinaria-Socug | Academic | 1 | Phase II | 0 |
New trials by year
2019
1
2020
1
2022
5
2023
4
2024
3
2025
5
2026
2