14
Registered trials
8
Recruiting
10
Unique sponsors
12
Unique IMPs
14
Commercial trials
Drug classes (ATC)
—
ATC code not specified
11
L
Oncology (ATC L)
2
S
Ophthalmology/ENT (ATC S)
1
Mechanism of action (INN-stem analysis)
Unknown / small molecule
7 substances
Kinase inhibitor
1 substance
Antimetabolite
1 substance
Taxane
1 substance
Checkpoint inhibitor (PD-1)
1 substance
Monoclonal antibody (tumor, humanized)
1 substance
Phase III:
2
Phase I/II:
1
Phase I:
7
Phase I (Other):
1
Phase I (First in Human):
3
Phase III
2 trials-
RecruitingMerck Sharp & Dohme LLC CommercialBELZUTIFAN; LENVATINIB
-
PendingRevolution Medicines Inc. Commercial(12M)-(1S,2S)-N-((63S,4S,Z)-11-ETHYL-12-(2-((S)-1-METHOXYETHYL)-5-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-3-YL)-10,10-DIMETHYL-5,7-DIOXO-61,62,63,64,65,66-HEXAHYDRO-11H-8-OXA-2(4,2)-THIAZOLA-1(5,3)-INDOLA-6(1,3)-PYRIDAZINACYCLOUNDECAPHANE-4-YL)-2-METHYLCYCLOPROPANE-1-CARBOXAMIDE
Phase I/II
1 trial-
RecruitingMerck Sharp & Dohme LLC CommercialPEMBROLIZUMAB; SACITUZUMAB TIRUMOTECAN
Phase I
7 trials-
RecruitingAmgen Inc. CommercialIMP not specified
-
EndedBeigene Ltd. CommercialIMP not specified
-
RecruitingBeOne Medicines AG CommercialIMP not specified
-
PendingMerck Healthcare KGaA CommercialIMP not specified
-
RecruitingNovartis Pharma AG CommercialIMP not specified
-
RecruitingNovartis Pharma AG CommercialIMP not specified
-
EndedPfizer Inc. CommercialIMP not specified
Phase I (Other)
1 trial-
EndedAmgen Inc. CommercialIMP not specified
Phase I (First in Human)
3 trials-
EndedAmgen Inc. CommercialAMG 193
-
RecruitingEir Biotherapies S.r.l. CommercialAUTOLOGOUS HUMAN ADIPOSE PERIVASCULAR STROMAL CELLS GENETICALLY MODIFIED TO SECRETE SOLUBLE TUMOUR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND; GEMCITABINE; PACLITAXEL ALBUMIN-BOUND
-
RecruitingITM Oncologics GmbH Commercial177LU-DPI-4452; 68GA-DPI-4452; ACETAZOLAMIDE
Sponsor activity
| Sponsor | Type | Trials | Phases | Recruiting |
|---|---|---|---|---|
| Amgen Inc. | Commercial | 3 | Phase I, Phase I (Other), Phase I (First in Human) | 1 |
| Novartis Pharma AG | Commercial | 2 | Phase I | 2 |
| Merck Sharp & Dohme LLC | Commercial | 2 | Phase III, Phase I/II | 2 |
| Beigene Ltd. | Commercial | 1 | Phase I | 0 |
| BeOne Medicines AG | Commercial | 1 | Phase I | 1 |
| Merck Healthcare KGaA | Commercial | 1 | Phase I | 0 |
| Pfizer Inc. | Commercial | 1 | Phase I | 0 |
| Revolution Medicines Inc. | Commercial | 1 | Phase III | 0 |
| Eir Biotherapies S.r.l. | Commercial | 1 | Phase I (First in Human) | 1 |
| ITM Oncologics GmbH | Commercial | 1 | Phase I (First in Human) | 1 |
New trials by year
2022
1
2023
1
2024
3
2025
4
2026
2