Phase I/II – Other

632 trials 274 recruiting

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A clinical trial applying Regulatory T cells in kidney transplant recipients to investigate the safety and tolerability as an adjunctive the… Recruiting

2024-514398-23-00 Solid organ transplantation (Kidney) 2024-06-10
Multicentric trial on the use of combined therapy of Thiamine and biotine in patients with Huntington´s disease. Recruiting

2023-508637-14-00 Huntington´s disease. 2024-06-06
Safety and diagnostic performance of uPAR PET imaging in localised, untreated prostate cancer. Recruiting

2023-507111-35-00 Prostate Cancer 2024-06-03
A Phase 1b/2 Study of BGB-11417 as Monotherapy and in Various Combinations with Dexamethasone plus Carfilzomib, Dexamethasone plus Daratumum… Recruiting

2023-507751-30-00 relapsed or refractory multiple myeloma 2024-05-27
COMBINATORY IMMUNOTHERAPY-2 (COM-IT-2) A phase 2 randomised open two-arm study to assess the tolerability and efficacy of immunotherapy comb… Recruiting

2023-510089-28-00 Non-small cell lung cancer (Stage IV) 2024-05-22
A phase 1/2 multicenter open-label study to investigate treatment of hydroxyurea (HU) in combination with valproic acid (VPA) or 6- mercapto… Recruiting

2022-501992-15-00 Acute Myeloid Leukemia (AML) 2024-05-21
A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants with Chronic Mye… Recruiting

2023-507677-18-00 Chronic Myeloid Leukemia 2024-05-17
Long-Term Follow-Up of Subjects Treated With NTLA-2002 Recruiting

2023-507956-56-00 Hereditary Angioedema 2024-05-17
Long-Term Follow-up of Patients Treated with Miltenyi Cell and Gene Therapies Recruiting

2022-501648-14-00 Relapsed or refractory CD19 positive B cell malignancie 2024-05-05
Mesenchymal stromal cells treatment in Lyell syndrome: A pilot phase 1-2 open trial (LYSYME) Recruiting

2024-516404-42-00 Adults diagnosed with SJS-TEN with at least 10% of body 2024-04-15
HOVON 165 CLL: A prospective randomized phase I/II trial of venetoclax treatment (26 cycles) with 6 cycles or 12 cycles of epcoritamab in pa… Recruiting

2022-500305-40-00 Small Lymphocytic Lymphoma 2024-04-10
Evaluation of EXL01 a new Live Biotherapeutic Product to prevent recurrence of Clostridioides difficile infection in high-risk patients. LIV… Recruiting

2023-506232-32-00 Multiple recurrences of Clostridioides difficile infect 2024-04-08
An Open-Label Exploratory Study of Fosigotifator in Subjects with Vanishing White Matter Disease Recruiting

2023-505704-30-00 Vanishing White Matter disease 2024-03-22
A Modular Open-Label, Multi-Centre Phase 1/2 Dose-Finding, Optimisation, and Expansion Study to Evaluate the Safety,Tolerability, Pharmacoki… Recruiting

2023-507738-26-00 Breast Cancer 2024-03-20
Safety and feasibility of immuno-OCT Recruiting

2023-506395-27-00 Barrett's esophagus 2024-03-15
Phase I/IIa multicentre study of infusion of autologous peripheral blood T lymphocytes expanded and genetically modified using Sleeping Beau… Recruiting

2024-514544-90-00 Relapsed or refractory B-cell lymphoma 2024-03-11
A Phase 1/2, Open-Label, Randomized, Dose Finding and Dose Expansion Study of Gedatolisib in Combination with Darolutamide in Metastatic Cas… Recruiting

2023-505898-32-00 Metastasic Castration-Resistant Prostate Cancer (mCRPC) 2024-02-28
A study in men with advanced prostate cancer to determine the safety and effects of a test drug (Lutetium (177Lu) rhPSMA 10.1 injection) Recruiting

2024-511537-35-00 Metastatic castration-resistant prostate cancer (mCRPC) 2024-02-09
Allogeneic CARCIK-CD19 in adults/pediatric B-cell Non Hodgkin Lymphoma or Chronic Lymphocytic Leukemia Recruiting

2023-505511-20-00 B-Non Hodgkin Lymphoma and Chronic Lymphocytic Leukemia 2024-01-29
Clinical Trial with Adipose Tissue Stem Cells on Biological Matrix for the Treatment of Venous Ulcer of the Lower Limbs. Recruiting

2024-513151-33-00 Venous ulcer of the lower limbs 2024-01-19
Combining anti-PD-L1 immune checkpoint inhibitor durvalumab with TLR-3 agonist rintatolimod in patients with metastatic pancreatic ductal ad… Recruiting

2024-514597-42-00 Metastatic pancreatic cancer 2024-01-16
Neoadjuvant trastuzumab, pertuzumab and tucatinib without chemotherapy in HER2-positive breast cancer: the TRAIN-4 study Recruiting

2024-518192-61-00 Breast cancer 2023-12-08
International proof of concept therapeutic Stratification trial of Molecular Anomalies in Relapsed or Refractory HEMatological malignancies … Recruiting

2022-501869-41-00 Acute Lymphoblastic Leukemia, in Relapse Lymphoblastic 2023-11-14
A study to examine the safety, tolerablity, body distribution and efficacy of [90Y]Y-PentixaTher therapy in CNS lymphoma patients. Recruiting

2024-512097-98-00 Central nervous system (CNS) lymphoma; recurrent or ref 2023-11-07