Phase I/II – Other

632 trials 274 recruiting

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Boosting recovery through excitation of arousal and awareness in comatose patients (BREA2KTHROUGH) Not authorised

2023-503617-30-01 Coma and other disorders of consciousness due to acute
PET/CT imaging with FAPI as a biomarker for the distinction between predominant active fibrotic and inflammatory phenotypes in patients with… Not authorised

2023-503686-26-00 Progressive Pulmonary Fibrosis (PPF)
A phase I/IIa, prospective, mono-center, double-blinded, randomized, controlled study to assess the safety and efficacy of applying PLX-PAD … Not authorised

2023-504212-15-00 Osteoarthritis
A phase I/II trial of ABTL0812 in children with relapsed/refractory neuroblastoma and other solid tumours Not authorised

2023-504246-64-00 Relapsed/refractory neuroblastoma and other solid tumou
Dose expansion, safety and efficacy study of intravesical instillation of TARA-002 in adults with high-grade non-muscle invasive bladder can… Not authorised

2023-505062-28-00 Non-muscle invasive bladder cancer
Safety, tolerability, and efficacy of mFOLFIRINOX ±BNT321 as adjuvant therapy following curative resection in patients with pancreatic adeno… Not authorised

2023-506014-47-00 Resected (R0 or R1) pancreatic ductal adenocarcinoma
Allogenic mesenchymal stem cell intraarticular injection for knee osteoarthritis therapy, an RCT explorative mode-of-action study Not authorised

2023-506088-33-00 knee osteoarthritis
LIGHTBEAM-U01 Substudy 01B: A Phase 1/2 Substudy to Evaluate the Safety and Efficacy of Pembrolizumab in Combination with Investigational Ag… Not authorised

2023-507179-23-00 Hematologic Malignancies or Solid Tumors in Pediatric a
Evaluation of treatment effectiveness and safety of somatic cell based therapy for urinary incontinence in patients after radical prostatect… Not authorised

2023-509812-27-00 urinary incontinence
Clinical trial of selinexor plus gemcitabine in selected advanced soft-tissue sarcomas Not authorised

2024-514827-40-00 Patients with advanced soft-tissue sarcoma (leiomyosarc
Safety, Tolerability, and Imaging Quality of HarMono-T Contrast Agent During Ultrasound of the Kidney in Healthy Subjects Not authorised

2024-514924-17-00 Ultrasound contrast agent, for diagnostic purposes (to
A study to investigate WEF-001 in patients with Advanced KRAS-Mutant Solid Tumours. Not authorised

2024-518644-21-00 Advanced KRAS- Mutant Solid Tumours
A seamless, phase 1b/2 multiple ascending dose/proof of concept study of XTMAB-16 in patients with pulmonary sarcoidosis with or without ext… Not authorised

2022-502877-41-00 Pulmonary sarcoidosis with or without extrapulmonary ma
A study to find how well budoprutug (TNT119) works and how safe it is in participants with immune thrombocytopenia Not authorised

2024-519745-30-00 Immune Thrombocytopenia (ITP)
PHASE I/IIa CLINICAL TRIAL FOR THE TREATMENT OF GRAFT VERSUS HOST DISEASE WITH A NEW GENERATION OF MESENCHYMAL STROMAL CELLS ECTOPICALLY EXP… Not authorised

2025-523139-21-00 Patients who have developed acute GVHD refractory to co
Tumour heterogeneity studies based on dedicated breast PET using proliferation radiotracers: early detection of the treatment response. Pending

2024-512152-38-00 Breast cancer
Therapeutic approach of repeated transient blood-brain barrier opening in amyotrophic lateral sclerosis Pending

2024-513471-40-00 Amyotrophic lateral Sclerosis
Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary D… Pending

2024-516085-11-00 Chronic Obstructive Pulmonary Disease
CAT-01 Pending

2024-517594-24-01 Cervical carcinoma
Research on two creams (Monobenzon / Imiquimod) together with the standard treatment for advanced or metastatic melanoma (ImMI). Pending

2024-520052-19-04 Malignant Melanoma
AdaptNK –Cell Therapy for High-risk Myeloid Disease Pending

2025-521962-83-00 Relapsed and/or refractory AML or MDS
NEurotrophins MImetic compound for modulation of ischemia/reperfusion damage in Liver transplantation with Extended criteria Donors, a phase… Pending

2023-508977-10-00 Liver Transplant
New therapeutic approach to Toxic Epidermal Necrolysis (TEN) using anti-CD38+ antibodies in the active phase of the disease – Phase I/II stu… Pending

2024-512164-63-00 Toxic Epidermal Necrolysis
The PACMAN-Hu19 trial: a phase I/II study with locally produced CD19-targeted CAR T-cell therapy Pending

2023-507597-40-00 B-cell precursor ALL