Phase I/II – Other

632 trials 274 recruiting

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FIDES: Focused Ultrasound-mediated Blood-Brain Barrier Opening In Pontine Diffuse Midline Glioma (DMG) to Enhance Systemic Therapy with Temo… Pending

2025-520814-78-00 Diffuse Midline Glioma, H3K27-altered
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy… Pending

2025-521145-24-01 Active Idiopathic Inflammatory Myopathy including derma
Study of the safety and efficacy of asciminib in pediatric and young adult participants with r/r Ph+ or ABL-class Ph-like ALL Pending

2025-522019-40-00 relapsed or refractory BCR::ABL1-positive (Philadelphia
HOVON 178 WM: Treatment of Waldenstrom’s macroglobulinemia with epcoritamab if the disease comes back during or after previous treatment Pending

2025-522295-91-00 relapsed or refractory Waldenstrom’s macroglobulinemia
A clinical trial of ifinatamab deruxtecan in people under age 18 who have certain types of cancer (MK-9999-01D) Pending

2025-522339-32-00 Neoplasm malignant
A Phase 1b/2, Multicenter, Randomized, Double-blind, Placebo-controlled Study of IM-101 in Adult Participants with Generalized Myasthenia Gr… Pending

2025-522406-20-00 Generalized Myasthenia Gravis and Ocular Myasthenia Gra
Multi-centre Phase 1/2 study testing LB-208 for adults with relapsed/refractory AML or high-risk MDS Pending

2025-523396-38-00 Relapse or refractory (r/r) acute myeloid leukaemia (AM
TGD001 Treatment in Thrombotic Microangiopathies Pending

2025-523802-34-00 Immune-Mediated Thrombotic Thrombocytopenic Purpura
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202) Pending

2025-523997-18-00 Sarcoma
COLOMBE - A multicentre, single arm, phase 1/2 study, aiming to assess the safety and efficacy of nivolumab and imiquimod combination in vul… Pending

2025-524759-29-00 Vulvar Squamous Cell Carcinoma (VSCC) patients
A Study to Test a New Drug in Adults With Moderate to Severe Ulcerative Colitis Recruiting

2025-524719-35-00 Ulcerative Colitis 2026-05-22
A Study of YL201 in Combination with Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors Recruiting

2025-523742-27-00 Advanced solid tumors 2026-04-28
MATRIX-IPC 2022-029 A phase I/II study evaluating Tuvusertib (M1774), an ATR Inhibitor, in combination with fulvestrant in hormone receptors… Recruiting

2023-507485-10-00 advanced breast cancer 2026-04-21
A study to test the safety and disease progression following YTB323 (rapcabtagene autoleucel) administration in participant with progressive… Recruiting

2024-514006-31-00 Non-active Progressive Multiple Sclerosis (PMS) 2026-04-16
A clinical study of MK-1084 with other treatments for non-small cell lung cancer (MK-3475-01F) Recruiting

2024-512248-47-00 Non-small Cell Lung Cancer (NSCLC) 2026-04-15
A clinical study of MK-3120 in people with bladder cancer (MK-3120-003) Recruiting

2025-520467-40-00 High-risk non-muscle invasive bladder cancer (NMIBC) wi 2026-03-16
Late immunity following single immunization with GA2 sporozoites (GACHA) Recruiting

2025-524045-27-00 Falciparum malaria 2026-03-11
A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies Recruiting

2024-516476-15-00 Advanced gastrointestinal stromal tumor (GIST) 2026-03-04
A clinical study of new treatments given with enfortumab vedotin and pembrolizumab in people with urothelial cancer (MK-3475-04D) Recruiting

2025-522253-19-00 Urothelial carcinoma 2026-02-11
Evaluation of Novel Thrombolytic TGD001 in Patients With Acute Ischemic Stroke Recruiting

2025-522455-26-00 Acute Ischemic Stroke 2025-12-17
A PHASE II, SINGLE-CENTER, RANDOMIZED DOUBLE BLIND, PLACEBO CONTROLLED STUDY TO EVALUATE THE EFFECT OF THE COMBINED THERAPY OF EH-301 AND N-… Recruiting

2024-519857-13-00 Amyotrophic Lateral Sclerosis (ALS) 2025-11-25
An open-label study to assess the safety, efficacy, and cellular kinetics of YTB323 (rapcabtagene autoleucel) in Relapsingin Relapsing Multi… Recruiting

2024-512714-18-00 Relapsing Multiple Sclerosis 2025-11-11
Clinical study of ruxolitinib and venetoclax for children with relapsed or refractory leukemia or lymphoma with mutations in the IL-7R/JAK-S… Recruiting

2022-501867-42-01 Acute Lymphoblastic Leukemia, in Relapse Lymphoblastic 2025-09-08
An Early Phase Clinical Trial to Evaluate COM701 in Relapsed Platinum Sensitive Ovarian Cancer (PSOC) Recruiting

2025-521125-33-00 Ovarian Cancer 2025-09-05