Phase I – Other

1,064 trials 249 recruiting

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of XmAb24306 in Combination with Cevostamab in Patients with Relapsed/Refract… Ended

2023-505212-38-00 Relapsed/Refractory Multiple Myeloma 2022-11-16
Phase 1b Study of Dato-DXd in Combination with Immunotherapy with or without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cance… Ended

2023-505992-54-00 Advanced or Metastatic Non-small Cell Lung Cancer (NSCL 2022-10-21
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-… Ended

2023-506871-88-00 Relapsed/Refractory Multiple Myeloma 2022-10-07
First-line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects with Extensive Stage Small Cell Lung Cance… Ended

2024-511021-58-00 Extensive Stage Small cell lung cancer (ES-SCLC) 2022-08-02
A Phase 1b Study of Bleximenib in Combination with AML Directed Therapies for Participants with Acute Myeloid Leukemia Harboring KMT2A or NP… Ended

2023-506582-58-00 Acute Myeloid Leukemia 2022-07-21
A Study to Evaluate Safety, Pharmacokinetics, and Activity of Cevostamab as Monotherapy and Cevostamab Plus Pomalidomide and Dexamethasone o… Ended

2023-507019-36-00 Relapsed or Refractory Multiple Myeloma (R/R MM) 2022-07-08
A Phase 1b Study of Bispecific T Cell Redirection Antibodies in Combination with Checkpoint Inhibition for the Treatment of Participants wit… Ended

2022-502681-24-00 Relapsed or Refractory Multiple Myeloma 2022-06-22
A study to test whether different combinations of BI 765063, ezabenlimab, chemotherapy, cetuximab, and BI 836880 help people with head and n… Ended

2024-512799-36-00 head and neck squamous cell carcinoma (HNSCC) 2022-06-16
A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblasto… Ended

2023-506719-17-00 Glioblastoma 2022-05-10
Master Protocol of Sotorasib (AMG 510) in Subjects with Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreaK 101) Ended

2023-506794-35-00 Advanced Solid Tumors Kirsten Rat Sarcoma (KRAS) pG12C 2022-04-01
A Multi-arm Phase 1b Study of Talquetamab With Other Anticancer Therapies in Participants with Multiple Myeloma Ended

2023-503620-60-00 multiple myeloma 2021-12-22
A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ez… Ended

2024-514034-20-00 non-small cell lung cancer or 2021-11-16
Study to Evaluate the PK and Safety of Oral Decitabine and Cedazuridine in Cancer Patients with Hepatic Impairment Ended

2024-516292-33-00 Myelodysplastic syndrome (MDS) 2021-10-22
A study to determine the safe dose of iberdomide (CC-220) in combination with R-CHOP21 and CC-98282 in combination with R-CHOP21 in subjects… Ended

2023-506094-35-00 Newly diagnosed aggressive B-cell lymphoma (a-BCL) 2021-09-17
Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children with Neurofibro… Ended

2024-517216-29-00 Neurofibromatosis Type 1 (NF1) Related Plexiform Neurof 2021-08-06
A Phase I Study of Belantamab Mafodotin in Multiple Myeloma Participants with Normal and Impaired Renal Function Ended

2023-506063-34-00 Relapsed/Refractory Multiple Myeloma 2021-07-23
A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Alone and in Combination With Ruxolitinib in Participants Wit… Ended

2023-507274-40-00 Myelofibrosis 2021-04-22
A Multi-arm Phase 1b Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma Ended

2023-503440-14-00 Relapsed/Refractory Multiple Myeloma 2021-03-08
A Phase 1b, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of MEDI5752 in C… Ended

2023-509604-15-00 Advanced Renal Cell Carcinoma 2021-02-15
An extension study to learn if bepranemab (UCB0107) is safe over a long period in adults with progressive supranuclear palsy Ended

2024-510951-36-00 Progressive Supranuclear Palsy 2020-11-16
EMBER: A Study of LY3484356 in Patients with Breast or Other Non-Breast Cancers Ended

2023-506785-32-00 Breast Cancer 2020-09-11
A Clinical Study to Evaluate the Safety and Pharmacokinetics of JNJ- 73841937 (Lazertinib), a Third Generation EGFR-TKI, as Monotherapy or i… Ended

2023-506577-35-00 Advanced Non-Small Cell Lung Cancer 2020-09-08
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma Ended

2024-512102-25-00 Neuroblastoma 2020-07-29
An Open-label, Multicenter, Phase 1b Study of OV-1001 (Cusatuzumab; Anti-CD70 Monoclonal Antibody) in Combination with Background Therapy fo… Ended

2024-513276-17-00 Acute Myeloid Leukemia 2020-07-01