Phase I – Other

1,064 trials 249 recruiting

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A Phase 1, Multi-Cohort, Open-Label, Randomized Pilot Study to Evaluate the Effect of Food and a Proton-Pump Inhibitor (esomeprazole) on the… Ended

2025-523370-16-00 Parkinsonian syndromes 2025-11-17
A Trial to Determine if Quabodepistat is Processed Differently in Adults with Reduced Liver Function Compared to Adults with Normal Liver Fu… Ended

2025-521502-18-00 Tuberculosis 2025-11-13
An open, single arm, single-center, Phase 1 trial investigating the effect of 7-days-repeated administration of linaprazan glurate on the ph… Ended

2024-518194-34-00 Helicobacter pylori infection, GERD 2025-11-11
A study investigating the safety, absorption, and elimination of RO7795081, a new compound that may potentially be used in the treatment of … Ended

2025-522766-78-00 Not Applicable 2025-11-10
A study to find out whether the medication pasireotide is absorbed and processed the same way when given under the skin using either a reusa… Ended

2024-519165-22-00 Post-bariatric hypoglycaemia 2025-11-04
A study in healthy people to test whether BI 3000202 affects how 2 other medicines (rosuvastatin and digoxin) are taken up in the body Ended

2025-520656-29-00 Healthy volunteer trial 2025-11-03
Phase 1 Study to Determine the Effect of CYP Induction Following Administration of Nirogacestat in Healthy Men Participants Ended

2025-521402-18-00 Desmoid tumor 2025-10-24
A randomised, double-blind, placebo-controlled phase Ib trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of … Ended

2025-522287-32-00 Depression 2025-10-22
Assessment of the safety and effects on the body of investigational products when used on psoriatic skin Ended

2025-522446-51-00 Plaque psoriasis 2025-10-17
A Trial to Evaluate the Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Insulin GZR33 Compared with Insulin Degludec at stea… Ended

2025-523052-32-00 Type 1 diabetes Mellitus 2025-10-17
Multiple-Ascending Doses of 2-Methoxyestradiol in Healthy Non-Pregnant Female Participants. Ended

2025-523419-12-00 No medical condition. 2025-10-15
A PHASE 1, OPENLABEL, SINGLECENTER STUDY TO EVALUATE DRUGDRUG INTERACTIONS WITH GEMFIBROZIL, ITRACONAZOLE, AND CARBAMAZEPINE AND THE FOOD-EF… Ended

2025-521508-23-00 Adrenoleukodystrophy 2025-10-10
A study in healthy people to test how itraconazole influences the amount of BI 3031185 in the blood Ended

2025-520654-10-00 Healthy volunteer trial 2025-10-06
A randomised, open label, three periods, three-treatment crossover study to evaluate the pharmacokinetics of alendronic acid oral formulatio… Ended

2025-522606-20-00 Pharmacokinetic study in healthy volunteers under faste 2025-10-06
Single dose, open-label, laboratory blinded, randomized, 2-treatment, 2-period, 2-sequence, crossover, pivotal study to assess the comparati… Ended

2025-522254-39-00 Bioavailability study in healthy volunteers under fed c 2025-09-29
Research into new test methods to measure pain with two existing drugs (nefopam and oxycodone) Ended

2025-522389-66-00 (Chronic) pain 2025-09-24
RANDOMIZED, CROSSOVER, TWO-PERIOD, COMPARATIVE BIOAVAILABILITY STUDY OF TWO IBUPROFEN FORMULATIONS, AFTER A SINGLE ORAL DOSE OF 400 MG IN SO… Ended

2025-520852-27-00 Healthy volunteers 2025-09-18
A Study to Investigate the Effect of RO7504109 on Immune Cells in Healthy Participants Ended

2025-522181-71-00 Not Applicable (N/A) 2025-09-17
A Study to Learn if Multiple Doses of the Study Medicine Called Carbamazepine Changes How the Body Processes the Other Study Medicine PF-072… Ended

2025-522331-34-00 locally advanced or metastatic ER+/HER2- breast cancer 2025-09-15
Evaluation of the Effect of Food, Itraconazole, and Rifampicin on the Single-Dose Pharmacokinetics of Naronapride. Ended

2024-520215-40-00 No medical condition. 2025-09-09
"A study in healthy people to test how 2 different formulations of a combination treatment (vicadrostat and empagliflozin) are taken up in … Ended

2025-521650-42-00 Healthy volunteer trial 2025-09-04
Randomized, open-label, three-period crossover study on the palatability of oral dispersible formulations of Zonisamide in healthy volunteer… Ended

2025-522297-36-00 Healthy volunteers 2025-09-03
A study comparing different RO7269162 capsules and investigating the effect of food on the uptake, breakdown, and elimination of RO7269162 i… Ended

2025-520616-33-00 Not Applicable 2025-09-02
Neoadjuvant Lu-PSMA radioligand therapy and Ipilimumab in men with very high-risk prostate cancer (NEPI) Ended

2024-514386-19-00 Patients with very high-risk prostate cancer (as define 2025-08-25