Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Feasibility study of Neo-adjuvant (before surgery) versus Adjuvant (after surgery) chemotherapy in Upper Tract Urothelial Carcinoma Under evaluation

2024-514991-41-01 Upper Tract Urothelial Carcinoma. Upper urinary tract t
A Study of Disitamab Vedotin Alone and with Pembrolizumab in Urothelial Cancer That Expresses HER2 Not authorised

2022-500030-28-00 Urothelial carcinoma
A Parallel-group (2-Arm), Randomized, Double-blind, 12-week Trial to Evaluate the Efficacy and Safety of MC2-25 Cream and MC2-25 Vehicle in… Not authorised

2022-500044-38-00 Chronic Kidney Disease associated Pruritus
Senolytics to Improve Osteoporosis therapy: A randomised controlled clinical trial The SENIOR Trial Not authorised

2022-500669-28-00 Osteoporosis
A Randomized, Placebo-controlled, Double-blind, Parallel group, 6 Month Study to Evaluate the Safety, Tolerability, and Potential Efficacy o… Not authorised

2022-500828-30-00 Early Alzheimer´s Disease
Phase2, double-blind, randomized, placebo-controlled, multicentre study to evaluation the safety, efficacy, and pharmacokinetics of TAK-242 … Not authorised

2022-501026-37-00 ACLF is a syndrome that occurs in patients with chronic
A 3-month, phase 2, single-blind, randomised, no-treatment controlled study assessing efficacy and safety of Renaparin® for improvement of k… Not authorised

2022-501389-23-00 end-stage renal disease or otherwise an insufficient ki
Early detection of triple negative breast cancer relapse (CUPCAKE) Not authorised

2022-501562-22-00 Triple-negative breast cancer (TNBC) patients at high r
A Study to Assess if BIIB080 Can Change Clinical Dementia Rating-Sum of Boxes Scores, and BIIB080 Safety and Tolerability When Injected Into… Not authorised

2022-501644-15-00 Mild Cognitive Impairment due to Alzheimer's Disease Al
Atorvastatin in episodic migraine Not authorised

2022-502176-23-00 Migraine
Atorvastatin in chronic migraine (StainMigChronic) Not authorised

2022-502177-42-01 Chronic migraine
A Phase IIa, Open Label Study to Evaluate the Safety of Afamelanotide in Patients with Early Parkinson's Disease Not authorised

2022-502207-30-00 Parkinson's Disease
Efficacy and Safety of ANB032 in the Treatment of Subjects with Atopic Dermatitis Not authorised

2023-503522-40-00 Atopic Dermatitis
[68Ga]Ga-FAPI total body PET/CT for improving diagnostic sensitivity and preoperative staging in gastroesophageal cancer and pancreatic canc… Not authorised

2023-503632-41-00 Pancreatic cancer and gastroesophageal cancer (esophagu
A Masked, Multicentre, Placebo-controlled, Randomized Phase IIa Clinical Trial to investigate the safety and efficacy of ApTOLL in a populat… Not authorised

2023-503751-97-00 STEMI (ST Elevation Myocardial Infarct)
A pharmacokinetics and safety study of cefiderocol in hospitalized pediatric patients from birth to less than 3 months of age with suspected… Not authorised

2023-503757-35-00 Aerobic Gram-negative bacterial infections
Estudio enmascarado, controlado con placebo, aleatorizado, piloto, de ApTOLL para el tratamiento de pacientes con ictus isquémico agudo a ni… Not authorised

2023-504015-32-00 Acute Ischemic Stroke (AIS)
Safety and efficacy of oral semaglutide in hyperglycaemic patients after renal transplantation Not authorised

2023-504159-29-00 Hyperglycaemia after renal transplantation
Phase 1b/2a Study to Evaluate Alnuctamab in Combination with Mezigdomide in Relapsed and/or Refractory Multiple Myeloma. Not authorised

2023-504367-16-00 Relapsed and/or Refractory Multiple Myeloma
ASPIRE-1: dApagliflozin SC0062 and Prevention of renal Injury; a Randomized Evaluation Not authorised

2023-504404-28-00 Chronic Kidney Disease
Trial of Cannabidiol for the treatment of alcohol dependence Not authorised

2023-504439-42-00 alcohol dependence
Trial of Cannabidiol for the treatment of alcohol dependence Not authorised

2023-504439-42-01 alcohol dependence
A geroscience approach to post-acute COVID-19 syndrome (PACS) by Diet and Exercise plus rapamycin or metformin to treat Frailty and restore … Not authorised

2023-504641-32-00 Post-acute COVID syndrome(PACS) diagnosis.
Improving inpatient GHB detoxification with baclofen Not authorised

2023-506167-34-00 GHB use disorder