Phase II/III (Integrated)

392 trials 186 recruiting

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An open-label, pharmacokinetic, safety, and efficacy study (Part I, single cycle) and double-blind, efficacy, non inferiority, and safety st… Recruiting

2024-514321-39-00 Chemotherapy-induced nausea and vomiting 2025-05-06
Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chem… Recruiting

2023-505773-32-00 Untreated Metastatic Non-Squamous Non-Small Cell Lung C 2025-03-25
68-Ga-FAPI-46 positron emission tomography (PET) to better visualise pancreatic and bile duct cancer. Recruiting

2024-516486-36-00 cholangiocarcinoma (bile duct cancer) 2025-03-24
AntaMIn - Pain reduction for limb injuries in pediatric emergency departments: A Randomised Clinical Trial comparing intranasal Fentanyl or … Recruiting

2023-506803-25-01 urgency 2025-02-26
A randomized, phase II/III trial on the biological and clinical effects of acetyl-L-carnitine in ALS Recruiting

2023-509853-29-00 amyotrophic lateral sclerosis 2025-02-24
FAPIDO Recruiting

2024-512059-19-00 Diverse oncological patients with a clinically challeng 2025-02-14
ASIC Channels and Migraine Disease - Proof-of-Concept Study on the Efficacy of Amiloride in Migraine Aura Prophylaxis Recruiting

2024-516044-25-00 Migraines with aura 2025-02-13
Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disor… Recruiting

2024-516306-28-00 Autism with Spectrum Disorders and Moderate to Severe I 2025-02-12
A phase II, multicenter, open-label study evaluating Glofitamab in combination with Venetoclax plus Zanubrutinib or Venetoclax alone in subj… Recruiting

2023-506706-40-00 Mantle-Cell Lymphoma 2025-02-11
Ozone treatment in patients with numbness and/or tingling secondary to chemotherapy. Randomized clinical trial. Recruiting

2024-517196-20-00 Paresthesia (numbness, tingling) secondary to chemother 2025-02-07
BONG: Reducing severe Breathlessness with Dronabinol in the severe and very severe chronic obstructive pulmonary disease patient group Recruiting

2024-513593-22-00 Chronic obstructive pulmonary disease 2025-01-31
CXCR4-directed [68Ga]Ga-PentixaFor PET/CT vs AVS performance in a diagnoStic randomized Trial Ultimately comparing hypertenSion outcome in p… Recruiting

2024-512628-12-00 Primary aldosteronism 2025-01-28
A study of aficamten (CK-3773274) in a Pediatric Population with Symptomatic Obstructive Hypertrophic Cardiomyopathy Recruiting

2024-511377-30-00 SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY 2025-01-23
Dopaminergic disruption induced by traumatic coma: multimodal neuroimaging approaches to characterize dopaminergic pathways abnormalities an… Recruiting

2023-504893-39-00 Comatose Traumatic Brain Injury patients 2025-01-14
Efecto de la inmunoterapia en pacientes con cáncer de pulmón de células no pequeñas oligometastásico (número limitado de metástasis) después… Recruiting

2023-508741-40-00 Non-small cell lung cancer 2025-01-14
ZELA trial: Phase 2b/3 Multicenter Study to Evaluate the Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developi… Recruiting

2024-513420-41-00 prematurity in neonates 2025-01-09
EvER-ILD 3 : Evaluation of Efficacy and safety of Rituximab and mycophenolate mofetil combination in patients with Interstitial Lung Disease… Recruiting

2023-510507-21-00 Intersitial lung disease related to systemic sclerosis 2025-01-08
The effect of a booster vaccination on protection against the mpox virus: is a booster vaccination with a lower dose as effective as the sta… Recruiting

2024-510697-24-00 mpox (earlier: monkey pox) 2025-01-02
Advancing the quality of treatment and care for acute agitation in emergency psychiatry Recruiting

2023-510201-18-00 acute agitation 2024-12-27
REPROGRAM-02 : Induction Regorafenib in combination with metronomic cyclophosphamide, capecitabine, and low-dose aspirin followed by chemoth… Recruiting

2024-516709-22-00 metastatic colorectal cancer carcinoma 2024-12-16
Efficacy of IMP reducing liver fibrosis in patients with advanced fibrosis due to alcohol: a randomized, double-blind, placebo-controlled cl… Recruiting

2024-519968-41-00 Fibrosis liber, chronic liver disease, alcoholic liver 2024-12-11
Short versus long antiplatelet therapy after TAVI Recruiting

2023-508208-40-00 All adult patients with successful transfemoral trans-a 2024-11-21
Specifying the Anti-inflammatory Effects of Ziltivekimab (SPIDER) Recruiting

2024-515893-29-01 Coronary artery disease 2024-11-19
Single-arm interventional study with ruxolitinib and AIEOP-BFM 2017 Poland or AIEOP-BFM 2017 standard of care chemotherapy in children with … Recruiting

2024-518316-39-00 Acute lymphoblastic leukemia 2024-11-18