Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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A Phase 2, Dose-Ranging Study of LY4100511 (DC-853) in Adult Participants with Moderate-to-Severe Plaque Psoriasis Ended

2024-512207-39-00 Plaque Psoriasis 2025-01-30
A randomised, double-blind, placebo controlled, parallel group, multi-centre trial in adult subjects with newly diagnosed type 1 diabetes me… Ended

2023-506545-27-01 Diabetes mellitus, Type 1 2025-01-28
A trial to learn how well NMS-01940153E works in combination with atezolizumab and priming administration of decitabine or with atezolizumab… Ended

2024-516737-12-00 Unresectable Hepatocellular Carcinoma (HCC) 2025-01-28
Efficacy of tocilizumab in the treatment of acute anterior ischemic optic neuropathy optic neuropathy in Horton's disease Ended

2024-519977-20-00 Acute Anterior Ischemic Optic Neuropathy associated wit 2025-01-27
A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 Ended

2024-511112-24-00 Narcolepsy Type 1 2025-01-17
Dendritic cell therapy combined treatment in multiple sclerosis Ended

2024-519975-24-00 Multiple sclerosis 2025-01-13
PEMBROLIZUMAB IN MMR-PROFICIENT METASTATIC COLORECTAL CANCER PHARMACOLOGICALLY PRIMED TO TRIGGER DYNAMIC HYPERMUTATION STATUS - THE ARETHUSA… Ended

2024-518526-33-01 Metastatic colorectal cancer 2025-01-09
A Multicenter, Randomized, Placebo-Controlled, Parallel Group Trial on the Safety and Efficacy of Istaroxime for Cardiogenic Shock SCAI Stag… Ended

2023-507243-11-02 Cardiogenic Shock 2025-01-05
Cannabidiol for reducing drinking in alcohol use disorder and modifying the effects of alcohol on the brain and the liver Ended

2024-517751-13-01 Psychiatric disorders 2024-12-26
A Phase 2 open-label imaging study to explore the effects of sonelokimab in patients with active axial spondyloarthritis Ended

2024-513498-36-00 axial spondyloarthritis 2024-12-23
With Ponatinib on the track for treatment-free-remission in chronic myeloid leukemia Ended

2024-518971-76-00 chronic myeloid leukemia in chronic phase 2024-12-21
Once-weekly petrelintide versus placebo for obesity or overweight with comorbidities Ended

2024-512549-18-00 Weight management 2024-12-19
Effects of AZD5004 in adults who are living with obesity or overweight with at least 1 weight-related medical condition Ended

2024-513691-18-00 Participants living with Obesity or Overweight with at 2024-12-11
A Window of Opportunity (WoO) study evaluating pembrolizumab with or without olaparib in Tertiary Lymphoid Structures (TLS)-positive selecte… Ended

2024-513469-38-00 Undifferentiated pleomorphic sarcoma and Dedifferentiat 2024-12-10
A clinical study of sotatercept in people with pulmonary arterial hypertension (MK-7962-024) Ended

2024-512278-92-00 Pulmonary Arterial Hypertension (PAH) 2024-12-09
Randomised, double-blind study comparing the analgesic efficacy of a lidocaine-prilocaine combination with lidocaine alone as local anesthes… Ended

2024-515965-32-00 Subjects having local anesthesia for dental procedures. 2024-12-09
L19IL2/L19TNF in patients with non-melanoma skin cancer. Ended

2024-518530-92-00 Patients with high-risk, locally advanced (non-metastat 2024-12-09
A randomized, double blind, placebo-controlled, dose response, phase II, multicentre trial to evaluate the efficacy and safety of oral AP118… Ended

2024-514981-37-00 Rheumatoid Arthritis 2024-12-05
A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjögren’s Syndrome Ended

2023-507680-19-00 Sjögren’s Syndrome 2024-11-28
Phleum pratense and Dactylis glomerata allergen extracts. Determination of the in vivo histamine equivalent prick test units. Ended

2024-514215-98-00 Allergy to Phleum pratense and Dactylis glomerata. 2024-11-26
A 14-week, multicentre, double-blind, randomised, placebo-controlled phase II study with an 8-week treatment period to assess the efficacy a… Ended

2024-513104-34-00 Major Depressive Disorder 2024-11-25
Is dermal measles-mumps-rubella-vaccine administration better than regular injection? Ended

2023-503845-79-01 Measles, mumps, and rubella 2024-11-24
Mangafodipir - an intracellular contrast agent for Magnetic Resonance Imaging (MRI): Measuring manganese uptake rate in heart failure patien… Ended

2023-508118-40-01 Heart Failure 2024-11-22
Evaluation of the decolonization rate and acceptance of a complete nasal decolonization kit with povidone iodine for MRSA patients Ended

2022-500642-25-00 MRSA patients 2024-11-21