Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Open-label, Multi-centre, Non-Inferiority study of safety and immunogenicity of BIMERVAX as heterologous booster for the prevention of coron… Ended

2023-504639-42-00 SARS-CoV-2 infection 2023-05-26
Biomarker Phase II Study Of Cabozantinib In Advanced Radioactive-Iodine Refractory Differentiated Thyroid Cancer. Ended

2024-511292-15-00 Advance Radioactive-Iodine Refractory Differentiated Th 2023-05-25
Phase 2 Study of Encorafenib and Binimetinib Plus Pembrolizumab in Participants With BRAF V600E/K Mutation-Positive Melanoma Who Progressed … Ended

2023-509471-17-00 Metastatic or unresectable locally advanced BRAF V600E/ 2023-05-24
Study of M5049 in DM and PM Participants (NEPTUNIA) Ended

2022-501351-82-00 Dermatomyositis, Polymyositis 2023-05-23
A research study to look at how a new medicine called NNC6019-0001 works and how safe it is for people who have heart disease due to TTR amy… Ended

2023-506824-96-00 The present study will include a population of patients 2023-05-23
A Phase 2 Open-label Study of Loncastuximab Tesirine in Combination with Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Patients wi… Ended

2022-501601-12-00 Diffuse large B-cell Lymphoma 2023-05-22
A Phase 2a Safety, Tolerability, and Pharmacodynamic Study of OMT-28 in PMD patients with myopathy and/or cardiomyopathy and inflammation (P… Ended

2023-508541-41-00 Primary Mitochondrial Disease 2023-05-22
GALOP : Oral glibenclamide in hyperglycaemia of the premature infant Ended

2024-512230-15-00 Transient hyperglycaemia in premature infants 2023-05-20
STUDY TO EVALUATE THE SAFETY AND EFFICACY OF BEMNIFOSBUVIR AND RUZASVIR IN PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION Ended

2023-504566-28-00 Chronic Hepatitis C Virus (HCV) Infection 2023-05-19
A Phase 2 Study of the Effects of Ponsegromab on Health-Related Quality of Life and Safety in Patients With Heart Failure (GARDEN-TIMI 74) Ended

2023-509747-27-00 Heart failure 2023-05-18
An open-label, single-arm, pilot study of Venetoclax in combination with 5 days Azacitidine in treatment-naïve subjects with acute myelogen… Ended

2022-501537-23-00 Acute myeloid leukemia 2023-05-16
A Phase 2 trial to evaluate the efficacy and safety of daxdilimab in participants with primary discoid lupus erythematosus. Ended

2023-509746-35-00 Primary Discoid Lupus Erythematosus 2023-05-16
Clinical study to assess safety and efficacy of rapamycin in paediatric high grade glioma Ended

2024-515951-39-00 high grade glioma 2023-05-16
A Study of Two Dose Levels of Vobramitamab Duocarmazine in Participants with Metastatic Castration-resistant Prostate Cancer (TAMARACK) Ended

2022-501078-20-00 Metastatic Castration-resistant Prostate Cancer 2023-05-15
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of VE202 in Patients with Mild-to-Moderate Ulcerative Colitis Ended

2024-512558-40-00 Mild-to-moderate ulcerative colitis 2023-05-11
Neo-adjuvant Pembrolizumab in vulvar squamous cell carcinoma: a clinical proof-of-concept study Ended

2024-512862-32-00 Vulvar squamous cell carcinoma 2023-05-11
Study to Evaluate the Safety, Pharmacokinetics, and Dose Response of Paltusotine Treatment in Subjects with Carcinoid Syndrome Ended

2024-511922-30-00 Carcinoid Syndrome 2023-05-11
A Multicenter, Open-Label, Evaluator-Blinded, Randomized Study to Evaluate the Safety and Tolerability of Single-Dose IV Oritavancin for the… Ended

2024-516385-10-00 Acute Bacterial Skin and Skin Structure Infections 2023-05-02
A Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 given by subcutaneous injection in adult participants with non-cirrhoti… Ended

2023-509704-14-00 Non-cirrhotic non-alcoholic steatohepatitis with fibros 2023-04-28
This is a phase 2, randomized, double blind, multicenter study evaluating the efficacy and safety of the combination of methotrexate plus UV… Ended

2024-512766-34-00 Vitiligo with new lesions or extension of old lesions d 2023-04-28
A Phase 2b study of TAK-755 (rADAMTS13) with minimal to no plasma exchange in the treatment of patients with thrombotic thrombocytopenic Pur… Ended

2023-507787-39-00 Immune-mediated thrombotic thrombocytopenic purpura (iT 2023-04-27
Evaluation of Amivantamab Infusion Related Reaction Mitigation Ended

2023-506578-11-00 EGFR-mutated Advanced or Metastatic Non-small Cell Lung 2023-04-25
A study of efficacy and safety of various treatments in participants with idiopathic pulmonary fibrosis (IPF) Ended

2023-508729-28-00 Idiopathic pulmonary fibrosis 2023-04-25
A Phase 2, Open-Label, Multicenter, Basket Study Evaluating the Safety and Efficacy of Brexucabtagene Autoleucel in Adults with Rare B-cell … Ended

2022-501259-10-00 Relapsed/Refractory Waldenstrom Macroglobulinemia (WM) 2023-04-14