Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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An Open-Label, Phase 2 Trial of Nanatinostat in Combination with Valganciclovir in Patients with Epstein-Barr Virus-Positive (EBV+) Relapsed… Ended

2024-512717-41-00 Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory 2021-10-01
A clinical study of tulisokibart for the treatment of ulcerative colitis (MK-7240-005) Ended

2023-509741-12-00 Ulcerative Colitis 2021-09-23
Myocarditis Therapy with IL-1 inhibitor (MYTH-1): a double-blind, phase IIa, placebo-controlled, randomized clinical trial to evaluate the e… Ended

2024-515472-13-00 endomyocardial biopsy (EBM)-proven virus-negative myoca 2021-09-23
Therapeutic strategy driven by residual disease for CARCIK-CD19 in patients with relapsed/refractory B cell precursor Acute Lymphoblastic Le… Ended

2024-519394-19-00 B cell precursor Acute Lymphoblastic Leukemia 2021-09-22
7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors Ended

2023-505284-36-00 Advanced solid tumors 2021-09-13
Metformin Intervention in children and adolescents with obesity. A parallel, three arms, randomized, 6 months, multi-center study with metfo… Ended

2024-517787-29-00 Children and Adolscents with obesity. 2021-09-09
A Phase 2 Study Evaluating Futibatinib (TAS-120) Plus Pembrolizumab in the Treatment of Advanced or Metastatic bladder, urethra or pelvis ca… Ended

2024-513760-26-00 Advanced or Metastatic Urothelial Carcinoma 2021-09-07
Evaluation of the feasibility of PD L 506 for stereotactic interstitial photodynamic therapy (iPDT) in adult patients with newly diagnosed s… Ended

2023-510024-79-00 Glioblastoma 2021-09-03
Research study on whether a combination of 2 medicines (NNC0194-0499 and Semaglutide) works in people with non-alcoholic steatohepatitis (NA… Ended

2023-506961-74-00 Non-alcoholic steatohepatitis (NASH) 2021-08-31
A study to learn how safe bimekizumab, how well it works and how it moves through the bloodstream in adolescents with moderate to severe pla… Ended

2023-509832-24-00 Moderate to Severe Plaque Psoriasis 2021-08-30
Study to investigate the efficacy and safety of allo-APZ2-CVU on wound healing of therapy-resistant chronic venous ulcer (CVU) Ended

2023-510162-27-00 Chronic venous ulcers (CVU) 2021-08-18
OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure (OPRA-HF) Ended

2024-511502-24-02 High-risk hyperkalemia 2021-08-18
Phase 2 First-Line ES-SCLC Platform Study Ended

2023-506538-56-00 First-line treatment of participants with extensive-sta 2021-08-12
A Phase 2 Study of ALX148 in Combination with Pembrolizumab in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03) Ended

2023-508340-22-00 metastatic or unresectable, recurrent HNSCC 2021-08-11
A Phase 2 study of ALX148 in Combination With Pembrolizumab and Chemotherapy in Patients with Advanced Head and Neck Squamous Cell Carcinoma… Ended

2023-508342-17-00 metastatic or unresectable, recurrent HNSCC 2021-08-11
The COlchicine HypERtENsion Trial Ended

2024-511391-32-00 Cardiovascular disease 2021-08-10
Integrative analysis of the tumor microenvironment and optimization of the immunotherapy duration in non-small cell lung cancer patients. Ended

2023-509490-23-00 Patients with locally advanced or metastasic Non-Small 2021-08-03
Phase I/II, Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM14 in Combination with Irinotecan in Pretreated Patients with S… Ended

2024-514890-24-00 Patients with Selected Advanced Solid Tumors 2021-07-23
Study of efficacy, safety, and tolerability of LNA043 in patients with symptomatic knee osteoarthritis Ended

2023-509937-37-00 Osteoarthritis 2021-07-21
Access to Pirfenidone Solution for Inhalation (AP01) for Treatment of Progressive, Fibrosing Interstitial Lung Diseases, including Idiopathi… Ended

2024-515964-30-00 Interstitial Lung Diseases (ILD), including but not lim 2021-07-14
Phase 2 Study of MK-1308A (Coformulated MK-1308/MK-3475), plus Lenvatinib (E7080/MK-7902) in First-line Therapy of Advanced Hepatocellular C… Ended

2023-505698-34-00 Hepatocellular carcinoma 2021-07-13
Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Ended

2023-503387-16-00 Classical Hodgkin Lymphoma 2021-07-13
Tucatinib and trastuzumab in solid tumors with HER2 alterations Ended

2024-511481-37-00 Previously Treated, Locally-Advanced Unresectable or Me 2021-07-12
A single patient trial with Ataluren in one case of severe common variable immunodeficiency with autoimmunity due to homozygous stop codon m… Ended

2024-518919-19-00 LRBA deficiency due homozygous nonsense mutations. It i 2021-07-09