Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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How does the antibiotic cefadroxil work in treating serious Staph infections? A first look Recruiting

2025-522547-17-00 staphylococcus aureus bacteremia 2026-01-04
LuMIERE: A Phase 1/2, Multicenter, Open label, Non randomized Study to Investigate Safety and Tolerability, Pharmacokinetics, Dosimetry, and… Recruiting

2023-508995-12-01 Recurrent or metastatic non-small cell lung cancer (NSC 2025-12-24
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of Vosoritide in Infants and … Recruiting

2024-512261-14-00 Hypochondroplasia 2025-12-22
A proof of concept study to evaluate treatments´efficacy by monitoring Minimal Residual Disease using ctDNA in HR-positive/HER2-negative ear… Recruiting

2023-505661-89-00 Early-stage, Hormone Receptor (HR)-positive / Human Epi 2025-12-19
A clinical study to investigate if the investigational product, called LN -145 (also known as Tumor Infiltrating Lymphocytes) is safe and be… Recruiting

2024-510778-26-00 Metastatic Non-Small-Cell Lung Cancer 2025-12-19
RAGNAR: Refractory Advanced diGestive Neuroendocrine carcinomas treated with tARlatamab Recruiting

2024-514327-42-00 Advanced neuroendocrine carcinomas (NECs) of the digest 2025-12-18
A randomized controlled phase II, double blinded trial to investigate pulmonary function after treatment with rituximab compared to placebo … Recruiting

2024-517667-23-00 Granulomatous Lymphocytic Interstitial Lung Disease (GL 2025-12-17
HER2 molecular imaging with 89Zr-trastuzumab PET/CT as a predictive biomarker for antibody-drug conjugate sequencing in patients with advanc… Recruiting

2024-516253-49-01 advanced/metastatic HER2-positive breast carcinoma 2025-12-12
A multicenter, open-label, Phase 2 study of TYRA-300 in non-muscle invasive bladder cancer Recruiting

2025-521277-14-00 Non-muscle invasive bladder cancer (NMIBC) 2025-12-09
Phase 2 Study of LAD191 in Adults With Hidradenitis Suppurativa Recruiting

2025-521293-34-00 Moderate-to-severe hidradenitis suppurativa 2025-12-09
A Study to Assess the Efficacy and Safety of RO7790121 in Patients with Moderate to Severe Rheumatoid Arthritis who have not Responded to or… Recruiting

2025-521034-28-00 Moderate to Severe Rheumatoid Arthritis (RA) 2025-12-05
RVU120 Rollover Study Recruiting

2025-521673-14-00 Relapsed / Refractory Metastatic or Advanced Solid Tumo 2025-12-03
Phase 2a Study of VX-407 in Subjects with ADPKD Who Have a Subset of PKD1 Gene Variants Recruiting

2024-517393-13-00 Autosomal Dominant Polycystic Kidney Disease (ADPKD) 2025-12-02
Randomized Study to Evaluate Melphalan/HDS Treatment Followed by Trifluridine–tipiracil plus Bevacizumab Versus Trifluridine–tipiracil plus … Recruiting

2024-520356-24-00 Refractory Metastatic Colorectal Cancer with Liver Domi 2025-12-01
Phase II study on the safety and feasibility of stool transplants in limited non-small cell lung cancer patients, using donors who responded… Recruiting

2025-521251-24-00 Non-Small cell lung cancer (NSCLC) 2025-12-01
PIRTOBRUTINIB AND GLOFITAMAB IN MANTLE CELL LYMPHOMA Recruiting

2024-512922-27-00 Mantle Cell Lymphoma (MCL) 2025-11-25
Upfront trastuzumab-deruxtecan plus capecitabine and bevacizumab for patients with HER2 positive metastatic colorectal cancer: the CHIMERA t… Recruiting

2024-519479-24-00 metastatic colorectal cancer 2025-11-21
IL-6 aGVHD Siltuximab: A phase II study to assess the efficacy and tolerability of siltuximab plus corticosteroids in first line treatment o… Recruiting

2024-510924-38-00 Grade III/IV acute graft versus host disease of the liv 2025-11-19
Role of the noradrenergic system in the regulation of learning dynamics: evaluation of the effect of a low-dose selective noradrenaline reup… Recruiting

2025-520959-90-00 Healthy subjects with no neurological or psychiatric di 2025-11-18
Randomized phase 2 study of Simvastatin in patients with ARID1A mutated advanced gastrooesophageal carcinoma treated with Nivolumab and Oxal… Recruiting

2024-519591-39-00 advanced or metastatic gastrooesophageal carcinoma HER2 2025-11-11
A study evaluating persistence of the immune response of the adjuvanted RSV vaccine and the safety and immunogenicity following revaccinatio… Recruiting

2024-519730-23-00 Respiratory Syncytial Virus Infections 2025-11-10
PET-Based Imaging of Radiolabeled CIT-013 Recruiting

2025-522189-60-00 Inflammatory mediated immune diseases 2025-11-04
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor (BTKi) and a Bcell Lymphoma-2 Inhibit… Recruiting

2025-521088-10-00 Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia 2025-10-23
A study to understand the safety and benefit of AlloNK® with rituximab in patients with hard-to-treat rheumatic diseases Recruiting

2025-520461-41-00 Systemic Sclerosis (SSc) 2025-10-22