Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Study of HM15912 in subjects with Short Bowel Syndrome-associated Intestinal Failure Recruiting

2024-515160-32-00 Short Bowel Syndrome-associated Intestinal Failure (SBS 2022-02-02
Evaluation of an initial treatment with bevacizumab in combination with chemotherapy and then in combination with niraparib in maintenance i… Recruiting

2023-504166-37-00 Advanced ovarian, tubal or peritoneal cancer. 2022-02-01
Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten (CK-3773274) in Adults With Hypertrophic Cardiomyo… Recruiting

2023-508963-58-00 Symptomatic hypertrophic cardiomyopathy (HCM) 2022-01-31
An Italian multicenter trial with Temozolomide taken daily at low doses continuously in patients with well differentiated neuroendocrine neo… Recruiting

2024-510898-24-00 Patients with well differentiated neuroendocrine neopla 2022-01-14
Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer Patients Recruiting

2023-508594-84-00 Metastatic pancreatic adenocarcinoma 2022-01-11
A multicentre study evaluating the safety of reperfusion thrombolytic therapy with intravenous recombinant tissue plasminogen activator (rtP… Recruiting

2024-518509-17-00 Acute ischemic stroke 2022-01-10
InvestiGating the rOle of Growth Hormone in hepatic lipid metabolism in humans Recruiting

2024-518214-11-01 acromegaly 2022-01-01
Treatment with venetoclax consolidated with ibrutinib and rituximab to increase the possibility of minimal residual disease in patient with … Recruiting

2024-514687-33-00 Previously Untreated Chronic Lymphophatic Leukaemia 2021-12-21
Study evaluating the interest of imatinib treatment maintenance or interruption after at least 10 years of treatment in patients with locall… Recruiting

2024-512631-77-00 locally advanced or metastatic Gastrointestinal Stromal 2021-12-20
STUDY TO ASSESS THE SCHEMAS OF RETREATMENT WITH LUTATHERA® IN PATIENTS WITH NEW PROGRESSION OF INTESTINAL WELL-DIFFERENTIATED NEUROENDOCRINE… Recruiting

2024-511001-28-00 Neuroendocrine tumor 2021-12-13
Safety, efficacy and pharmacokinetics of sparsentan in pediatric subjects with selected kidney diseases. Recruiting

2023-505497-14-00 Proteinuric glomerular diseases including: •Focal segm 2021-12-09
Riluzole in spinocerebellar ataxia type 7 Recruiting

2024-518962-29-00 Spinocerebellar ataxia type 7 (SCA7) 2021-12-07
Short-term Pre-OPerative Durvalumab (MEDI 4736) in early small triple negative breast cancer patients (POP-Durva) Recruiting

2024-512082-14-00 Untreated small triple negative breast cancer 2021-12-06
An open-label Phase 2 trial to investigate efficacy and safety of intraamniotic administrations of ER004 to male subjects with X-linked hypo… Recruiting

2024-512632-30-00 X-linked hypohidrotic ectodermal dysplasia (XLHED) 2021-12-02
Multicenter phase II study of preoperative chemoradiotherapy with CApecitabine plus Temozolomide in patients with MGMT silenced and microsat… Recruiting

2024-513931-26-00 locally advanced rectal cancer (LARC) 2021-12-01
STOP-LEUKEMIA: Repurposing metformin as a leukemia-preventive drug in CCUS and LR-MDS Recruiting

2024-518436-37-01 Myelodysplastic syndromes (MDS), very low- and low-risk 2021-12-01
An Investigator-Initiated, Phase II, Multicenter, Open-Label, Single-Arm, Prospective Clinical Trial to Evaluate the Efficacy and Safety of … Recruiting

2024-518263-35-00 Primary plasma cell leukemia 2021-11-23
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis an… Recruiting

2023-505825-15-00 Lupus Nephritis (LN) 2021-10-29
A Randomized & Observational phase II trial comparing the activity of TrabectedIn vs gemCitabine in patients with metastatic or locally adva… Recruiting

2024-513820-40-00 Metastatic or locally advanced leiomyosarcoma 2021-10-29
Prospective, randomized, open, multicenter Phase II trial to investigate the efficacy of trifluridine/tipiracil plus panitumumab versus trif… Recruiting

2024-513723-16-00 metastatic colorectal cancer 2021-10-21
TRIBECA - Multicenter randomized double-blind study comparing the efficacy and safety of belimumab in the treatment of non-infectious active… Recruiting

2024-516237-12-00 Cryoglobulinemia vasculitis 2021-10-20
Intra-arterial hepatic (IAH) infusion of radiolabelled somatostatin analogs in GEP-NET patients with dominant liver metastases Recruiting

2024-514785-39-00 Gastroenteropancreatic neuroendocrine tumours (GEP-NETs 2021-09-24
A Phase 2 Study to Test Effects of Using DAY101 in Children with Brain Cancer Recruiting

2024-510691-20-00 RAF-Altered, Recurrent or Progressive Low-Grade Glioma 2021-09-23
EXTENSION STUDY FOR PATIENTS WHO HAVE COMPLETED A PRIOR GLAXOSMITHKLINE/TESARO-SPONSORED NIRAPARIB STUDY AND ARE JUDGED BY THE INVESTIGATOR … Recruiting

2023-506618-29-00 Advanced ovarian, breast, or prostate cancer 2021-09-22