Phase III/IV (Integrated)

217 trials 105 recruiting

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Cognitive brain circuits and the spread of tau in vivo in humans Recruiting

2024-511613-38-01 Alzheimer disease in a preclinical and prodromal stage 2018-05-18
Panguian Recruiting

2023-503474-20-00 Rheumatoid arthritis 2017-11-10
RANDOMIZED CONTROLLED CLINICAL TRIAL EVALUATING METHOTREXATE OR LEFLUNOMIDE + TARGETED THERAPY VERSUS METHOTREXATE OR LEFLUNOMIDE + SULFASAL… Recruiting

2024-516704-41-00 Rheumatoid Arthritis 2016-03-30
Impact of long-acting injectable cabotegravir for HIV pre-exposure prophylaxis persistence and coverage in men who have sex with men in Fran… Ended

2024-510678-25-00 HIV prevention 2025-05-14
Multi-institutional Evaluation of the Cost-effectiveness of PSMA-PET/CT for the Detection of Pelvic Lymph Node Invasion in Newly Diagnosed P… Ended

2024-518171-59-00 Prostate Cancer 2025-01-23
Study to evaluate the use of durvalumab in combination with platinum-based chemotherapy followed by durvalumab with olaparib as first-line t… Ended

2024-514728-17-00 Advanced or recurrent endometrial cancer 2024-12-30
A Patient guided dose reduction strategy of tyrosine kinase inhibitors in chronic myeloid leukaemia: RODEO study Ended

2024-516511-24-00 Chronic myeloid leukaemia 2024-11-14
A study to learn how bimekizumab works in people with moderate to severe plaque psoriasis. Ended

2023-506333-29-00 Moderate to Severe Plaque Psoriasis 2024-10-01
A prospective randomized, single blind, controlled, safety and non-inferiority study of esketamine plus propofol compared to methohexital an… Ended

2024-512210-18-00 major depression 2024-08-01
A Phase 3b/4 Randomized, Double-Blind, Double-Dummy, Active Comparator-Controlled Study, Comparing the Efficacy and Safety of Upadacitinib V… Ended

2022-502578-18-00 Rheumatoid Arthritis 2023-11-07
A study to test whether spesolimab helps people with Generalized Pustular Psoriasis (GPP) who need treatment for repeated flares Ended

2022-502128-38-00 Generalized Pustular Psoriasis 2023-10-11
TRIO: A prospective randomized Trial of non-inferiority comparing RItuximab versus Ocrelizumab in relapsing-remitting multiple sclerosis. Ended

2022-501027-25-01 Multiple Sclerosis 2023-06-01
A PILOT PROOF-OF–CONCEPT STUDY TO ASSESS THE EFFICACY AND SAFETY OF A 6 MONTHS RAVULIZUMAB TREATMENT IN PATIENTS WITH FLARES OF CORTICOSTERO… Ended

2024-512154-24-00 IgA nephropathy 2023-05-26
Safety of ibuprofen after major orthopaedic surgeries Ended

2022-502502-32-00 Hip and knee arthroplasties 2023-04-17
Immunogenicity of 9-valent HPV vaccine in immunocompromised children and adolescents Ended

2022-501413-31-00 Immunosuppressed patients 2023-03-07
Personalized dosing of ocrelizumab in MS Ended

2024-513193-22-00 Multiple Sclerosis 2022-03-16
Pembrolizumab/placebo plus paclitaxel with or without bevacizumab for platinum-resistant recurrent ovarian cancer. Ended

2023-506177-35-00 Ovarian, fallopian tube, or primary peritoneal carcinom 2021-10-23
A rollover extension program (REP) to evaluate the long-term safety and tolerability of open label iptacopan in adult participants with prim… Ended

2023-508690-92-00 IgA Nephropathy 2021-09-20
An Open-Label Extension and long-term efficacy and safety monitoring study of patients with Crohn's disease previously included in the loss … Ended

2024-514326-23-00 Crohn's disease 2021-09-10
Long term access to berotralstat for HAE subjects from previous clinical trials. Ended

2024-511285-37-00 Hereditary Angioedema 2021-08-31
A study to investigate the efficacy and safety of trastuzumab deruxtecan in patients With or Without Brain Metastasis Who Have Previously-Tr… Ended

2024-510588-53-00 Treatment of patients with HER2-positive breast cancer 2021-06-10
Phase III study of Pembrolizumab plus chemoradiation vs chemoradiation along for patients with muscle invasive bladder cancer Ended

2023-503500-87-00 Muscle Invasive Bladder Cancer 2020-03-17
Maintaining or Stopping immunosuppressive Therapy in patients with ANCA vasculitis and End-stage Renal disease: a prospective, multicenter, … Ended

2024-512470-10-00 End-stage Renal disease 2018-02-02
Sentinel lymph node (SLN) detection in early oral cancer using Gallium-68-Tilmanocept PET/CT. Suspended

2025-521682-27-00 Oral cancer