Therapeutic Use (Phase IV)

1,197 trials 558 recruiting

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Impact of GLP1-RAs on inflammation and endothelial biomarkerS in Type 2 diABetes meLlitus patiEnts: STABLE-GLP1 trial. Pending

2025-520802-37-00 Type 2 diabetes mellitus
Assessing the efficacy of Elixirium thymi compositum in the treatment of acute bronchitis in pediatric patients (EXOTIC): A double-blind, ra… Pending

2025-520845-61-00 Acute bronchitis
MULTICENTER, RANDOMIZED STUDY TO EVALUATE THE EFFICACY OF INDIVIDUALIZATION OF IMMUNOLOGICAL RISK BASED ON SELECTIVE BIOMARKERS (HLA EPLE… Pending

2025-520884-42-00 Kidney Transplant
Short-Term Anticoagulation versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure. The ANDES s… Pending

2025-520954-12-00 Atrial Fibrillation Device thrombosis post-Left Atrial
Randomized clinical trial to assess the efficacy and safety of a strategy for primary prevention of cardiovascular disease in patients with … Pending

2025-521086-28-00 CHRONIC INFLAMMATORY RHEUMATIC DISEASE: rheumatoid arth
GLIFLOFASTER : EARLY GLIFLOZIN TREATMENT IN ELDERLY PATIENT HOSPITALIZED FOR DECOMPENSATED CHRONIC HEART FAILURE ADMITTED IN THE EMERGENCY … Pending

2025-521101-40-00 CHRONIC DECOMPENSATED HEART FAILURE
Prevenir el dolor en las primeras 24-48h después de una cirugía de la mama. Se aplica inyectando con jeringa a nivel local, un anestésico ll… Pending

2025-521162-10-00 Disminuir dolor en cirugía de mama
A biomarker enrichment trial of anti-EGFR agents in patients with advanced colorectal cancer (aCRC) with wild-type RAS and right primary tum… Pending

2025-521209-42-00 advanced colorectal cancer with wild-type RAS and right
An open-label, randomized clinical trial comparing Etacizin versus Propafenone in Atrial Fibrillation Pending

2025-521267-13-01 Atrial fibrillation
ENDO-67 project: Investigating ENDOcrine therapy-related questions using Ki67 changes in the window-of-opportunity before breast surgery Pending

2025-521385-10-00 Breast cancer
A Phase 4 Mechanistic Longitudinal Study to Evaluate the Impact of EARLY Risankizumab Treatment on TRM Cell Levels in Moderate-to-Severe Pso… Pending

2025-521424-30-00 Psoriasis
Pilot randomized controlled trial of the prevention of early respiratory tract infections in intubated patients. Comparison of the safety an… Pending

2025-521454-42-00 Reduced level of consciousness associated with severe t
Herpes zoster after recombinant herpes zoster vaccination - Immediate post-RHZ-vaccination evolution of CMI, HMI and lymphocyte count and ty… Pending

2025-521547-20-00 Herpes Zoster virus prevention
Reassessment of statin-associated muscle symptoms in adults with familial hypercholesterolemia Pending

2025-521589-83-00 Familial hypercholesterolaemia
REstoration with calcifediol of VItamin D deficiency in pulmonary Arterial Hypertension patients (REVIDAH study) Pending

2025-521694-14-00 Patients with diagnosis of Pulmonary Arterial Hypertens
DOSABEMA-Pharmacokinetic model of abemaciclib: correlation with severe diarrhea as the primary toxicity endpoint in patients with hormone re… Pending

2025-521696-31-00 HR+, HER2- breast cancer at high risk of recurrence
Platelet function testing in outpatients after heart transplantation on aspirin therapy Pending

2025-521699-71-01 Patients who have undergone heart transplantation.
Remimazolam versus propofol for deep sedation during Endoscopic Ultrasound (EUS) procedures. A randomized controlled trial. Pending

2025-521784-12-00 Gastric and pancreatic cancer
Effects of CLADribine tablets on the Immune Synapse, in Relapsing Multiple Sclerosis (RMS) patients_CLADIS. Pending

2025-521910-24-00 Multiple Sclerosis
Pharmacokinetic study of the use of Nefopam 30 mg tablet in patients suffering from acute pain in rheumatology - NEFOPAIN kinetics Pending

2025-521926-13-00 Hospitalized patient with acute rheumatological pain, r
Eficacy of epidural analgesia initiated with dural puncture epidural technic for labour with ultra-low concentration of levobupivacaine. Pending

2025-522071-28-00 Pregnant women who enter in the delivery room and reque
LOTUS Pending

2025-522111-42-02 muscle protein turnover hemodialysis
Study comparing two dosing methods of tocilizumab in patients with rheumatoid arthritis in remission or with low disease activity Pending

2025-522319-41-00 rheumatoid arthritis
Post-operative analgesia and spinal block duration following total hip arthroplasties Pending

2025-522358-38-02 Hip osteoarthrosis and postoperative pain