Centre Hospitalier Universitaire De Nantes — Sponsor Intelligence | 187 EU Trials

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187 Registered trials

101 Recruiting

43 Completed trials

6 Countries active

284 Unique IMPs

100% Results reported

Phase III

Phase II

Phase IV

Phase III: 50 Phase II/III: 9 Phase II: 68 Phase I/II: 8 Phase III/IV: 7 Phase IV: 28 Phase I: 3 Phase I (Other): 7 Phase I (FiH): 6 Other: 1

Oversight events:

1 serious breach 6 temporary halts 1 urgent safety measure 1 corrective measure across 9 trials

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100%

43 of 43 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Hepatocellular carcinoma 3 Asthma 3 Epidermolysis bullosa 2 Chronic kidney disease 2 Parkinson's disease 2 Vitiligo 2 Cerebral haemorrhage 1 Colorectal cancer metastatic 1 Intracardiac thrombus 1 Neurodevelopmental disorder 1 Perioperative analgesia 1 Primary progressive multiple sclerosis 1

Top IMPs

SODIUM CHLORIDE 9 TACROLIMUS 5 MYCOPHENOLATE MOFETIL 4 AMOXICILLIN, CLAVULANIC ACID 3 BORTEZOMIB 3 CLOSTRIDIUM BOTULINUM NEUROTOXIN TYPE A (150KD), FREE OF COMPLEXING PROTEINS 3 ISATUXIMAB 3 KETAMINE HYDROCHLORIDE 3 LENALIDOMIDE 3 MYCOPHENOLIC ACID 3 N,N-DIETHYL-(2-(4-(2-(18F)FLUOROETHOXY)PHENYL)-5,7-DIMETHYLPYRAZOLO(1,5-A)PYRIMIDINE-3-YL)ACETAMIDE 3 OXYGEN 3

All trials

187 total

Baricitinib for treating hospital-acquired pneumonia in critically ill patients with a proinflammatory phenotype, an international phase II … Not authorised

2023-503480-42-00 Phase II/III 4 countries BARICITINIB
Methotrexate treatment in hand osteoarthritis refractory to usual treatments Pending

2022-502362-24-00 Phase II 1 country FOLIC ACID; METHOTREXATE
Efficacy and Safety of Cryotherapy followed by Tirbanibulin ointment for actinic keratosis on the scalp and forehead Pending

2023-509931-15-00 Phase III/IV 1 country TIRBANIBULIN
ESP-BACK : Erector Spinae Plane Block for acute low back pain Pending

2024-511595-32-00 Phase IV 1 country
Safety study for the use of Rapamycin in children with familial adenomatous polyposis - RAPA-4-FAP Pending

2024-512079-11-00 Phase II 1 country SIROLIMUS
SPARE : Stopping Pneumonia Antibiotherapy Regimen Early Pending

2024-512236-30-00 Phase III 1 country
DESIRE MS: A prospective randomized non-inferiority trial comparing anti-CD20 maintenance versus De-Escalation Strategy In Relapsing-Remitti… Pending

2024-513292-40-00 Phase III 1 country
Osteoarticular infections on prosthesis: impact of three antibiotic therapies on the digestive microbiota Pending

2024-513298-29-00 Phase II 1 country CEFEPIME; CEFTOBIPROLE MEDOCARIL SODIUM; DAPTOMYCIN; PIPERACILLIN, TAZOBACTAM
A randomized, double-blind, placebo-controlled trial comparing the efficacy and tolerance of solriamfetol in patients affected with idiopath… Pending

2024-513365-39-00 Phase II 1 country
Ketamine infusion for symptomatological improvement of severe borderline personality disorder: a pilot study Pending

2024-514361-19-00 Phase II 1 country KETAMINE HYDROCHLORIDE
ANTIBIOBONTA - Assessment of the interest of a peri-operative antibiotic strategy applied to patients with asymptomatic bacteriuria undergoi… Pending

2024-515107-19-00 Phase III 1 country AMOXICILLIN; AMOXICILLIN, CLAVULANIC ACID; AZTREONAM; CEFIXIME; CEFTRIAXONE; CIP…
Safety and Efficacy of Neoadjuvant immunotherapy with Durvalumab (MEDI 4736) in combination with neoadjuvant chemotherapy (Gemcitabin/Cispla… Pending

2024-516077-72-02 Phase II 1 country CARBOPLATIN; CISPLATIN; DURVALUMAB; GEMCITABINE
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol Pending

2024-516232-10-00 Phase IV 1 country
A multi-center open-label phase 2 study of Ixazomib, Iberdomide and dexamethasone in elderly patients with multiple myeloma at first relapse Pending

2024-516257-44-00 Phase II 1 country DEXAMETHASONE SODIUM PHOSPHATE; IBERDOMIDE; IXAZOMIB CITRATE
Preoperative use of Romiplostim in thrombocytopenic patients undergoing cardiac surgery. A Phase 3, multicenter randomized double-blinded co… Pending

2024-517710-15-00 Phase II 1 country ROMIPLOSTIM; SODIUM CHLORIDE
LIDOCRIT : Effect of continuous intravenous LIDOCaine on discomfort in postoperative CRITical care inpatients Pending

2024-517749-15-00 Phase III/IV 1 country
RAPAMALYMPH protocol Pending

2024-517769-17-00 Phase II 1 country SIROLIMUS
Evaluation of Botulinum TOXin type A in the treatment of Buerger’s disease Pending

2024-517772-38-00 Phase II/III 1 country BOTULINUM TOXIN TYPE A - HAEMAGGLUTININ COMPLEX
A phase IIb, randomized, double-blind, multicenter study evaluating the efficacy of botulinum toxin versus placebo on pain and health relate… Pending

2024-517948-66-00 Phase II 1 country CLOSTRIDIUM BOTULINUM NEUROTOXIN TYPE A (150KD), FREE OF COMPLEXING PROTEINS
Rifampin-free regimen versus rifampin-containing regimen in the treatment of staphylococcal prosthetic valve endocarditis: a multicenter ran… Pending

2024-518018-22-00 Phase III 1 country CEFAZOLIN SODIUM; CEFTAROLINE FOSAMIL; DAPTOMYCIN; LEVOFLOXACIN; RIFAMPICIN; SUL…
Upper-limb Active Function and Botulinum Toxin A Pending

2024-518147-37-00 Phase II 1 country BOTULINUM TOXIN TYPE A - HAEMAGGLUTININ COMPLEX
DonneDvit : Assessing the Impact of a Mode of Vitamin D Supplementation on the Incidence of Hypercalciuria in Subjets Aged From 2 to 18 Year… Pending

2024-518219-20-00 Phase IV 1 country COLECALCIFEROL
Lidocaine for opioid sparing in vaso-occlusive crisis of Sickle Cell Disease Pending

2024-518437-28-00 Phase III 1 country
Efficacy and safety of allogenic cultured Adipose-derived mesenchymal stromal cell injections on MoUth fibrosis and handicap in patients wit… Pending

2024-518516-39-00 Phase II 1 country ALLOGENIC ADIPOSE-TISSUE-DERIVED MESENCHYMAL STEM CELLS; SODIUM CHLORIDE

Showing 1–24 of 187 trials

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