Clostridium Botulinum Neurotoxin Type A (150Kd), Free Of Complexing Proteins — Drug Intelligence | 24 EU Trials

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24 Registered trials

13 Recruiting

8 Completed trials

15 Sponsors

17 Countries

Phase III

Phase II

Phase IV

Phase III: 10 Phase II/III: 1 Phase II: 8 Phase IV: 5

Oversight events:

1 temporary halt 1 urgent safety measure 1 unexpected event 3 corrective measures across 4 trials

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Indications tested

Complex regional pain syndrome 1 Piriformis syndrome 1 Muscle spasticity 1

Sponsors using this IMP

Merz Therapeutics GmbH 5 Assistance Publique Hopitaux De Paris 4 Centre Hospitalier Universitaire De Nantes 3 Rigshospitalet 2 Amsterdam UMC Stichting 1 Azienda Ospedaliera Universitaria Integrata Verona 1 Dra. Nuria Gutierrez Dubón 1 Falck clinic 1 Frederiksberg Hospital 1 Fundacion Para El Fomento De La Investigacion Sanitaria Y Biomedica De La Comunitat Valenciana 1 Gentofte Hospital 1 Merz Aesthetics GmbH 1

All trials

24 total

Head-to-head comparison of six different botox products voor glabellar frown wrinkles. Pending

2024-516865-35-01 Phase IV 1 country Stichting Amsterdam UMC
A phase IIb, randomized, double-blind, multicenter study evaluating the efficacy of botulinum toxin versus placebo on pain and health relate… Pending

2024-517948-66-00 Phase II 1 country Centre Hospitalier Universitaire De Nimes
Satisfaction study of split doses botulinum toxin with double frequency Recruiting

2025-520915-14-00 Phase II/III 1 country Falck clinic
Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection via Hysteroscopy in Severe Primary Dysmenorrhea: A Prospecti… Recruiting

2025-520638-53-00 Phase III 1 country Centre Hospitalier Universitaire De Nantes
A clinical trial to evaluate efficacy and safety of Xeomin® injections for preventing chronic migraine Recruiting

2024-515682-34-00 Phase III 9 countries Merz Therapeutics GmbH
A clinical trial to evaluate efficacy and safety of Xeomin® injections for preventing episodic migraine Recruiting

2024-515715-22-00 Phase III 9 countries Merz Therapeutics GmbH
A Phase 3, randomized, parallel-group, double-blind, multicenter study investigating the safety and efficacy of NT 201 compared with placebo… Recruiting

2025-520499-24-00 Phase III 4 countries Merz Aesthetics GmbH
Botulinumtoxin A as a treatment for myalgia and myofacial pain in patient with temporomandibulardisorders – a quality study associated to a … Recruiting

2023-504033-44-00 Phase III 1 country Region Stockholm Folktandvarden
Botox Treatment for Patients with Hidradenitis Suppurativa: A Within-Person, Randomized, Double-blind, Controlled Study Recruiting

2024-519946-54-00 Phase IV 1 country Frederiksberg Hospital; Gentofte Hospital
Surgical treatment of large incisional hernia with botulinum toxin A injection: a double-blind randomized controlled trial Recruiting

2023-504554-35-00 Phase III 1 country Assistance Publique Hopitaux De Paris
Perineural injections of incobotulinumtoxin-A for diabetic neuropathic pain of the lower extremities: A double-blind, randomized, placebo-co… Recruiting

2022-500727-68-01 Phase II 1 country Rigshospitalet
Clinical trial to see the effect and safety of botulinum toxin type A with doses adapted to patients with severe spasticity Recruiting

2024-517668-51-01 Phase IV 1 country Dra. Nuria Gutierrez Dubón
PREPARE - Intrapapillary botulinum toxin injection for PREvention of post-surgical PAncREatic fistula Recruiting

2024-514929-33-00 Phase III 1 country Assistance Publique Hopitaux De Paris
Prospective, open-label, non-randomized, single-arm, dose titration study to investigate the efficacy and safety of IncobotulinumtoxinA in c… Recruiting

2024-518447-38-00 Phase II 1 country Azienda Ospedaliera Universitaria Integrata Verona
DEROTOX : DEgenerative ROtator cuff disease and botulinum TOXin Recruiting

2024-514074-40-00 Phase II 1 country Assistance Publique Hopitaux De Paris
Prospective, randomized, blinded, comparative study between botulinum toxin and topical capsaicin in the treatment of postmastectomy syndrom… Ended

2024-513609-29-01 Phase IV 1 country Fundacion Para El Fomento De La Investigacion Sanitaria Y Biomedica De La Comuni…
BOTAF - Prevention of post-operative Atrial Fibrillation by BOTulinum toxin injections into epicardial fat pads around pulmonary veins in pa… Ended

2024-513645-37-00 Phase III 1 country Assistance Publique Hopitaux De Paris
Study to compare the efficacy and safety of NT 201 (botulinum toxin) with placebo for the treatment of lower limb spasticity caused by strok… Ended

2023-505810-12-00 Phase III 9 countries Merz Pharmaceuticals GmbH
Perineural incobotulinumtoxin-A for Complex Regional Pain Syndrome - An open-label feasibility study (PINCom) Halted

2024-519832-17-00 Phase II 1 country Rigshospitalet
A clinical trial to investigate efficacy and safety of NT 201 injections compared with placebo injections in participants aged 18 years and … Ended

2022-501461-52-00 Phase II 6 countries Merz Therapeutics GmbH
Overactive Bladder Treatment with Xeomin and Vibe Delivery System (XAVIER) Ended

2022-501759-95-00 Phase II 1 country Vensica Medical Ltd.
Selän alueen poikkeava aktiivisuus servikaalisessa dystoniassa Ended

2024-517068-43-00 Phase IV 1 country Pirkanmaan hyvinvointialue
A clinical study to investigate the efficacy and safety of NT 201 in the treatment of lower limb spasticity in children and adolescents with… Ended

2023-503420-19-00 Phase III 2 countries Merz Pharmaceuticals GmbH
Assessment of Pain After Botulinum Toxin Injections in Osteoarthritis of the thumb Ended

2024-517280-23-00 Phase II 1 country Centre Hospitalier Universitaire De Nice

Showing 1–24 of 24 trials

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