Bacterial Infections and Mycoses

318 trials 133 recruiting

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Study to Assess the Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy in Adults With Complic… Ended

2024-515180-56-00 Complicated urinary tract infection (cUTI), acute uncom 5 2023-06-26
Pharmacokinetic study of minocycline in patients with nontuberculous mycobacterial disease Ended

2024-517758-87-00 Nontuberculous mycobacterial disease 2 2023-06-22
A Single Dose, Fast State, Bioequivalence Study of CEFIXIMA ATB 400 mg Hard Capsules (Antibiotice S.A.) vs. CEFIXORAL® 400 mg Film Coated Ta… Ended

2023-504011-33-00 healthy subjects 2 2023-06-12
Efficacy, Safety, Tolerability Study of LYR-210 Depot in Chronic Sinusitis Ended

2023-506268-15-00 Chronic Rhinosinusitis (CRS) in Adults 5 2023-06-05
Study to Assess the Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in the Treatment of C… Ended

2024-515463-55-00 Complicated urinary tract infection (cUTI) and acute un 5 2023-05-18
A Phase 1, Multicentre, Open-Label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single IV Dose of Rezafungin Acetat… Ended

2022-501985-23-00 Fungal infections 3 2023-05-18
A clinical study of the V116 vaccine for adults who have an increased risk for invasive pneumococcal disease Ended

2022-502791-22-01 Pneumococcal infection 5 2023-05-17
Safety and immune responses after vaccination with two investigational RNA-based vaccines against tuberculosis in healthy volunteers Ended

2023-509515-89-00 Tuberculosis 1 2023-04-14
Study of Two Treatment Regimens for Candidemia and/or Invasive Candidiasis: Intravenous Echinocandin followed by Oral Ibrexafungerp versus I… Ended

2024-511755-18-00 Invasive Candidiasis/ Candidemia 5 2022-12-23
Safety and efficacy of PC945 (opelconazole) in combination with other antifungal therapy for the treatment of refractory invasive pulmonary … Ended

2024-511281-36-00 Refractory Invasive Pulmonary Aspergillosis 5 2022-11-17
Safety and Immunogenicity of V116 in Adults 50 Years of Age or Older Ended

2022-503144-40-00 Pneumococcal disease 5 2022-11-17
Phase 3, Placebo-Controlled, Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Trial of a 6-Valent OspA-Based Lyme Disease… Ended

2023-509105-72-00 Active immunization against Lyme disease 5 2022-08-10
Epirubicin for the Treatment of Sepsis & Septic Shock Ended

2024-515776-12-00 Patients with sepsis or septic shock, currently hospita 4 2022-06-30
PhagoDAIR I : A Pilot, Multicenter, Randomized, Non Comparative, Double-Blind Study of Phage Therapy in Patients with Hip or Knee Prosthetic… Ended

2024-516207-17-00 knee or hip prosthetic joint infection (PJI) due to Sta 4 2022-06-15
A study to evaluate the efficacy and safety of olorofim versus AmBisome® for treatment of invasive aspergillosis Ended

2024-513030-38-00 Invasive fungal infections due to Aspergillus spp. 5 2022-02-15
A study to evaluate ExPEC9V vaccine for the prevention of Invasive E. coli Disease in adults aged 60 years and older with a history of urina… Ended

2023-506589-30-00 Invasive Extraintestinal Pathogenic Escherichia coli Di 5 2022-02-09
A randomized non-inferiority clinical trial of doxycycline vs BPG for early syphilis Ended

2024-513532-23-00 early syphilis 5 2021-12-06
MENACWY=MEN7B-003 Ended

2023-506449-40-00 Infections, Meningococcal 9 2021-11-29
Oral Alternative Antibiotics for Patients with Syphilis Ended

2024-514984-24-00 Syphilis 11 2021-10-07
Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to Assess Efficacy and Safety of D-P… Ended

2023-509698-21-00 Prevention of post abdominal surgery incisional infecti 5 2021-03-17
Adjunctive DobutAmine in sePtic cardiomyopathy with Tissue hypoperfusion: a randomized controlled multi-center trial Ended

2024-517839-50-00 sepsis 11 2020-09-20
A Phase 3 Study of Rezafungin for Injection Versus the Standard Antimicrobial Regimen to Prevent Invasive Fungal Diseases in AdultsUndergoin… Ended

2024-514471-18-00 Invasive Fungal Diseases in Adults undergoing Allogenei 5 2020-05-13
Rapid rEcognition of COrticosteroid Resistant or sentive Sepsis - RECORDS Ended

2024-516407-16-00 Patients admitted to the ICU proven or suspected infect 5 2020-04-10
Safety and pharmacokinetics of ceftolozane/tazobactam in pediatric participants with nosocomial pneumonia Ended

2022-501110-56-00 Nosocomial infection, Pneumonia 3 2020-02-26