Bacterial Infections and Mycoses

318 trials 133 recruiting

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Baricitinib for treating hospital-acquired pneumonia in critically ill patients with a proinflammatory phenotype, an international phase II … Not authorised

2023-503480-42-00 Hospital-acquired pneumonia 10
Individualized Multiplex Pathophysiological Treatment of Severe Acute Infections (IMPACT) Not authorised

2025-522215-42-00 Severe acute infection 6
A two part, randomized, double-blind, placebo-controlled, parallel group SAD and MD clinical study to evaluate the safety, tolerability and … Not authorised

2022-503145-22-00 Pseudomonas colonization 1
A pharmacokinetics and safety study of cefiderocol in hospitalized pediatric patients from birth to less than 3 months of age with suspected… Not authorised

2023-503757-35-00 Aerobic Gram-negative bacterial infections 4
Phase I-Ib clinical trial of safety and immunobiology of prophylactic infusion of lymphocytes and NK cells after Allo-HCT. Not authorised

2024-517002-28-00 graft-versus-host disease 3
A Randomized, Multicentre, Seamless, Adaptive Phase I/II Study to Determine Safety and Efficacy of RhinoPHAGE-2A cocktail in Patients with C… Not authorised

2024-516220-34-00 Chronic Rhinosinusitis associated with Staphylococcus a 7
ANTIMIDIS - Cefazolin mediastinal distribution using microdialysis Not authorised

2025-521988-13-00 Infection prophylaxis 6
A Phase I, Open-label, Randomized, Active-Controlled, to Evaluate the Safety and Immunogenicity of the DuoChol Oral Cholera Vaccine in 18 to… Pending

2025-522633-57-00 Prevention of Cholera disease 1
AMOXICILLIN VERSUS AMOXICILLIN-CLAVULANATE VERSUS PLACEBO IN ACUTE OTITIS MEDIA IN CHILDREN Pending

2025-524259-30-00 Acute otitis media 11
Optimising TREATment for severe Gram-Negative Bacterial infections. Pending

2025-521476-65-00 Severe Gram-Negative Bacterial infections 6
A monocentric Phase I pivotal pharmacology study for the determination of the local and systemic exposure of locally applied Minocycline in … Pending

2023-506126-36-00 Periodontitis 3
Adding oxygen to enhance antibiotic treatment of chronic lung infection Pending

2024-513197-22-02 Primary ciliary dyskinesia 3
Comparing the efficacy and safety of extended (3 h) and intermittent infusion (0.5 h) of beta-lactams (cefepime, ceftriaxone, meropenem, pip… Pending

2024-518115-19-02 suspected or proven infection 6
Nebulized Amikacine for Ventilator associated gram negative Pneumonia in ECMO veno-arterial patients: A randomized Pilot Study (NAVAP-ECMO) Pending

2023-509722-22-00 gram-negative bacillus pneumonia acquired during mechan 4
A randomized, double blind, double dummy, parallel group, multicenter clinical trial to evaluate the safety and clinical and microbiologic e… Pending

2024-518646-24-00 Uncomplicated urinary tract infection (uUTI) 11
A Phase 2, monocentric, prospective, nonrandomized, open-label, experimental study to evaluate efficacy and safety of intrabronchial instill… Pending

2025-523501-15-00 Simple aspergilloma 4
Clinical trial to assess the safety and tolerability of TP-122A for the treatment of ventilator-associated pneumonia. Pending

2025-521533-85-00 Ventilator-Associated Pneumonia 7
A Study to Learn About the Study Medicine Called Aztreonam-Avibactam in Neonates and Infants Less Than 9 Months of Age With Suspected or Con… Pending

2023-507757-15-01 Sepsis 4
Optimal Duration of Antibiotic Therapy in Drained Pyogenic Liver Abscess: 3 weeks versus 6 weeks, a non-inferiority trial Pending

2025-520940-14-00 Pyogenic liver abscess 6
Trial to confirm efficacy, safety, and clinical impact between the bacterial mucosal immunotherapy compared with placebo in women with local… Pending

2025-524377-16-00 Recurrent Non-Complicated Urinary Tract Infections (rUT 5
Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG® Pending

2025-522752-45-00 Complicated skin wounds (wounds healing per secundam vi 10
Feasibility of the Application of a new Six-month Treatment for multidrug-resistant tuberculosis (MDR-TB) patients in France (FAST-MDR) Pending

2024-512763-32-00 Patients diagnosed at the study sites with rifampicinre 5
PTX3 genetically stratified randomized double-blinded allocation event-driven clinical trial for antifungal prophylaxis in patients with acu… Pending

2024-517211-79-00 Antifungal prophylaxis in patients with acute myeloid l 6
E. coli Urinary Tract Infection Study Pending

2023-509777-23-00 Bacterial urinary infection 1